Cells and Tissues
This organelle contains the hereditary information of the cell
What is the Nucleus?
It is an inactive form of drug, which is converted to an active form after metabolism.
What is prodrug?
Nucleosomes consist of DNA and _____.
What are histones?
Whiplash injury results in damage to this ligament of the cervical spine.
What is the anterior longitudinal ligament?
Thyroid hormone in combination with epinephrine increases the liberation of fatty acids. This demonstrates which concept related to hormone action?
What is permissive action?
The number of hydrogen bonds between adenine and thymine.
What is the two?
It is a monoclonal antibody which neutralizes VEGF (Vascular Endothelial growth factor)
What is Bevacizumab and its mechanism of action?
These organelles contain catalase and break down very long chain fatty acids.
What are peroxisomes?
This muscle arises from ribs 3, 4 and 5 and is inserted into the coracoid process of the scapula
What is the pectoralis minor?
An unstable membrane potential seen in smooth muscle where cyclic depolarizations and repolarizations may remain below threshold or may result in action potential and are caused by fluctuations in sodium permeability
What is slow wave potential/BER?
These scientists received the Nobel prize for the discovery of the structure of DNA.
Who are Francis Crick, Maurice Wilkins and James Watson?
(Watson, Crick +/- Wilkins also acceptable)
It is done for drugs having narrow therapeutic index like digoxin, aminoglycosides, tricyclic antidepressants, theophylline, lithium, Phenytoin and immuno-modulators such as tacrolimus and cyclosporinetc
What is Therapeutic Drug Monitoring (TDM)?
The majority of cellular energy is generated via ____.
What is oxidative phosphorylation?
This vessel passes immediately over the ureter deep in the pelvis.
What is the uterine artery?
Norepinephrine, in turn, stimulates ______________, which mediate the effects on heart rate.
What are Beta-1 adrenergic receptors?
This type of cell death is seen in tuberculosis.
What is caseous necrosis?
It is the ratio of the dose that produces toxicity (LD50) to the dose that produces an efficacious response (ED50).
What is therapeutic index?
Secreted signals that affect proximal cells are referred to as ______.
What is paracrine signaling?
Blood from this chamber of the heart next passes through the tricuspid valve.
What is the right atrium?
Arteriovenous fistulas are direct connections (usually small) between arteries and veins that bypass the intervening _________.
What is Capillary?
This type of contractile tissue is found in the uterus.
What is smooth muscle?
This drug produces Torsades de pointes (QT interval Prolongation) and Cinchonism: (ringing in ears, deafness, vertigo, visual disturbances)
What are the adverse effects of Quinidine?
A mutation in this gene in flies disrupts the degradation-targeting complex and causes improper orientation of the body and wing hairs.
What is dishevelled?
This muscle is the most powerful extensor of the hip joint.
What is the gluteus maximus?
Fibromuscular dysplasia is a focal irregular ________ in medium and large muscular arteries, including renal, carotid, splanchnic, and vertebral vessels.
What is Thickening?