Cardiovascular
MSK
Respiratory
Child/Adolescent
Endocrinology
100
Which of the following statements concerning rehabilitation of the patient after an MI is (are) true? 

a) sexual intercourse should not resume for at least 3 months

b) patients who have sustained an MI should not work for at least 4 months

c) patients who have sustained an MI gradually may increase activity during 6 to 8 weeks

d) no significant psychological distress regarding the MI has been shown to occur in the patient's spouse or significant other

e) all of the above

What is c? 


Patients who have sustained an MI gradually may increase activity during 6 to 8 weeks. 

100

A 50-year-old right-handed female waitress with rheumatoid arthritis presents to your office complaining of pain in her right wrist. She tells you that the pain is 6/10, is worse at the end of the day after her shift and better when she doesn’t have to carry trays or dishes at work. Your physical exam shows tenderness to palpation at the radial styloid and pain that is exacerbated by grasping the thumb and abducting the hand toward the ulna. X-rays of the right wrist and hand are normal. What is the most likely diagnosis?


De Quervain’s disease is also called stenosing tenosynovitis of the abductor pollicus longus. 

Associated with RA, and 6 times more common in women

100

An elderly patient with a known history of CHF  develops an abnormal breathing pattern while asleep in her nursing home. This pattern consists of a repeated cycle of apnea followed by hyperpnea. 

What is Cheyne-Stokes respiration/breathing

100
By the time a child reaches 7 years of age, how many doses of Dtap should have been administered? 
5 doses.
100
Which of the following statements is FALSE regarding Hashimoto's thyroiditis? 

a) It is more common in women than men

b) antithyroid antibodies are found in the majority of individuals with this condition

c) symptoms of hyperthyroidism often precede symptoms of hypothyroidism

d) it is also known as chronic autoimmune thyroiditis

e) it is due to antibody-mediated destruction of circulating thyroid hormone. 

What is e?


The pathophysiology includes antibody and cell mediated destruction of the thyroid gland, not the thyroid hormone.

200
What is the single most important lipid risk factor for coronary artery disease (CAD), according to NCEP? 

a) elevated HDL level

b) elevated triglyceride level

c) elevated LDL level

d) depressed HDL level

e) elevated total blood cholesterol value

What is c? 


Elevated LDL level

200
Which of the following is not indicative of inflammatory back pain such as ankylosis spondylitis/

a. insidious onset

b. onset before age 40

c. morning stiffness

d. aggravation of pain with activity

e. pain for more than 3 months

d. 

improves with activity

200
Most common cause of stridor in children < 6months
what is 1. Laryngomalacia 2. Croup
200
A 6 week old infant has a temperature of 39 C and no abnormalities on physical examination. What are appropriate management strategies for this child? 

a) CBC, BCx, oral Amoxicillin, follow up in 10-14 days

b) CBC, BCx, IV ceftriaxone, follow up in 24 hours

c) CBC, BCx, UA and UCx, CSF culture, IV ceftriaxone and admission to the hospital

d) CBC, UCx, Oral water, Acetaminophen, follow up in 12-24 hours

What is C?


For febrile infants <3 months of age entire sepsis workup has to be done.

200
A 65 yo AAF with PMHx of iron-deficiency anemia, CHF with EF of 35%, and T2DM presents for diabetes follow up. Most recent A1c is 8.9%. Out of the following classes of medications, which one is contraindicated for her? 

a) Sulfonylureas

b) Biguanides

c) DPP-4 inhibitors

d) Thiazolidinediones

What is d? 


Thiazolidinediones

( e.g. Rosiglitazone, Pioglitazone) 

Mechanism of action: preserve beta cells from ongoing destruction.

SE: cause fluid retention (leading to heart failure); stimulate accumulation of adipose tissue

300
What is the most important characteristic found on echocardiography for a patient with systolic dysfunction?

a) myocardial hypertrophy

b) valvular heart disease

c) cor pulmonale

d) low ejection fraction

e) wall motion abnormalities

What is d? 


Low ejection fraction (<40%)

300

A 58-year-old female presents to the hospital complaining of pain and stiffness in her thighs and shoulders that seems to be worse in the morning. Her only medication is sertraline, which was started three weeks ago for depression. Physical examination reveals 5/5 muscle strength throughout. 

Polymyalgia Rhemuatica 


(pain and stiffness in proximal muscles that is worse in the morning or after prolonged inactivity. Other symptoms include fever, weight loss, fatigue, and depression. PMR typically presents in patients over the age of 50 years of age. Patients do not have decreased muscle strength, which helps to distinguish it from other disorders presenting with proximal muscle weakness, such as polymyositis or dermatomyositis.)

300
Mild COPD is defined by the following parameters: 

FEV1/FVC

FEV1


Gold Staging System: 

Stage I Mild: FEV1/FVC <0.70, FEV1 (postbronchodilator) >80% predicted

Stage II Moderate: FEV1/FVC <0.70, FEV1 (postbronchodilator) 59-79% predicated

Stage III Severe: FEV1/FVC <0.70, FEV1 (postbronchodilator) 39-49% predicated

Stage IV Very severe: FEV1/FVC <0.70, FEV1 <30% predicted or <50% predicated + respiratory failure

300

A 7-year-old boy presents with fever for 6 days. Examination reveals an uncomfortable child with erythema around the lips with cracking, bilateral conjunctivitis, a generalized rash and swelling of the hands. Labs show an elevated platelet count, CRP and ESR. Which therapy should be initiated?

IVIG (Kawasaki's Disease)
300

A 57-year-old type 2 diabetic man presents to his primary care provider for his annual physical. He was diagnosed with diabetes seven years ago and has a history of alcohol abuse. His most recent hemoglobin A1C was 7.9 percent and fasting glucose of 156. He is not on any diabetic medications. He states that two years ago he had an episode of intense mid-abdominal pain that radiated to his back. He has had two more similar episodes. Ever since then, he has constant epigastric pain and has noticed loose, foul smelling stools that float in the toilet. Considering his glycemic control and past medical history, what class of anti-hyperglycemic agents is contraindicated for this patient? 

Glucagon-like peptide-1 agonists


Risk of cholelithiasis, pancreatitis, pancreatic cancer

400
Which of the following does NOT reduce hospitalizations and mortality in patients with CHF? 

a) BB

b) CCB

c) Spironloactone

d) ACEi

e) Biventricular pacing

What is b?


CCB : have shown no mortality benefit or decreased hospitalization benefit for CHF patients

400

A 43-year-old-female comes to clinic with complaints of a flare in her arthritis. The patient states that she has been taking an oral medication, the name of which she cannot recall, but did remember her rheumatologist stating that it is a safe drug and is also used to treat malaria. She takes one pill twice a day. Based on the description of the medication the patient was likely taking, what does the appropriate monitoring required for use of this medication include?

a. CMP (LFT's)

b. retinal exam

c. CBC

d. annual PPD


retinal exam
400

32 African American man with chronic cough, bilateral hilar lymphadenopathy and pulmonary infiltrates on chest radiograph. Restrictive lung pattern with non-caseating granuloma formation. What is first line treatment for this diagnosis

Steroids (sarcoidosis) 
400

A 15 year old female presents to Akron Children's ED in moderate distress and a severe generalized rash. It is a maculopapular rash with confluent severe erythema associated with it. It is present on the palms, soles, dorsum of the hands, and extensor surfaces, trunk, abdomen, back, and there are some vesicular lesions present on the buccal mucosa. More than 50% of her skin is involved and Nikolsky's sign is positive. She is on Day 4 of Bactrim for a bad paranychial infection of the great toe. The diagnosis is ___

What is TEN? Toxic epidermal necrolysis

Stevens' Johnsons/Toxic epidermal necrolysis: peeling skin, mucosal lesions, could be macular, papular, vesicular or bullous in appearance. Common drugs: sulfa drugs, penicillin antibiotics, cefixime, barbiturates, lamotrigine, phenytoin, and trimethoprim. Common infections: Mycoplasma, EBV, CMV

SJS : <10% involvement of skin

TEN: >30% involvement of skin

400
A 24 year old man comes to your office with symptoms of extreme weakness, 20 pound weight loss, change in color of his skin, lightheadedness and dizziness. On exam, you notice hyper pigmentation, BP 90/70. Labs show sodium low at 115, Potassium high at 6.7, serum urea elevated at 9 , serum calcium elevated at 12. The diagnosis is ____

a) Conn's 

b) Cushing's

c) Addison's

d) Primary hyperparathyroidism

e) primary pituitary failure

What is c? 


Addison's = primary adrenocortical insufficiency. 

Symptoms: weakness, weight loss, hyperpigmentation, hypotension

Labs: hyperkalemia, hyponatremia, increased BUN, hypercalcemia, increased plasma ACTH, and DECREASED SERUM CORTISOL LEVEL. 

both short ACTH stimulation test and prolonged ACTH stimulation test yield no cortical response.

500

Ventricular septal defect (VSD) is the most common congenital heart defect, what condition is it most likely to be associated with?

a) Congenital rubella

b) Down's syndrome

c) Fetal alcohol syndrome

d) Maternal diabetes

What is FAS? 

VSD is associated with fetal alcohol syndrome. PDA is associated with congenital rubella. ASD (ostium primum type) is associated with Down's syndrome. Transposition of the great vessels is associated with maternal diabetes.

500

A 7-year-old female presents to your office with her mother for the complaint of painful right knee that has been intermittent for over three months. She denies any trauma, previous injury and her past medical history is otherwise negative. Further questioning also reveals mild photophobia in the right eye as well as right eye soreness and occasional blurry vision which has also been noted to occur in the left eye. ANA is positive. Most likely diagnosis?

Juvenile idiopathic arthritis (JIA)

500
What are the USPSTF guidelines for lung cancer screening? 


Give age range, criteria, modality of testing

The USPSTF recommends annual screening for lung cancer with low-dose computed tomography in adults ages 55 to 80 years who have a 30 pack-year smoking history and currently smoke or have quit within the past 15 years. Screening should be discontinued once a person has not smoked for 15 years or develops a health problem that substantially limits life expectancy or the ability or willingness to have curative lung surgery.

500
What are the guidelines for vision screening in children by the USPSTF? 


Give age range and frequency

The USPSTF recommends vision screening at least once in all children ages 3 to 5 years to detect amblyopia or its risk factors.

500
What are the guidelines for diabetes screening by USPSTF?


Give age range and criteria. 

The USPSTF recommends screening for abnormal blood glucose as part of cardiovascular risk assessment in adults aged 40 to 70 years who are overweight or obese. Clinicians should offer or refer patients with abnormal blood glucose to intensive behavioral counseling interventions to promote a healthful diet and physical activity.

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