Cell Physio/Structure
Hemostasis/Coag
Inflammation and Shock
Fluids/Electrolytes
Burns
100
What is/are the function(s) of the various phospholipids that compose the lipid bilayer of cell membranes? A) separates the intracellular space from the extracellular space B) serve as substrates for the formation of signal transduction molecules C) serve as signals to induce the phagocytosis of apoptotic cells D) A and B E) all of the above
E) all of the above
100
Which of the following substances is not known to directly activate platelets during the process of clot formation? A) thrombin B) ATP C) epinephrine D) collagen E) IL-6
E) IL-6
100
The cell type most characteristic of chronic inflammation is the: A) macrophage B) B cell C) NK cell D) neutrophil E) eosinophil
A) macrophage
100
All of the following symptoms are seen with hyper-magnesemia except: A) tachypnea B) depression of reflexes C) arrythmias D) HoTN E) CNS depression
A) tachypnea
100
A 52 year old male weighing 70 kg sustained a 65% total body surface area (TBSA) burn. What are his fluid requirements? A) 8000 cc in 24 hrs B) 18200 cc in 16 hrs C) 12800 cc in 24 hrs D) 9100 cc in 8 hrs
D) 9100 in 8 hrs
200
Which of these is not a function that is carried out by an integral membrane protein in a plasma membrane? A) receptor for growth factors B) pump for K+ C) channel for macromolecules D) structural protein E) determinant of membrane fluidity
E) determinant of membrane fluidity
200
Low molecular weight heparin (LMWH) produces its primary effects because of its inhibition of which factor? A) IIa B) IXa C) Xa D) XIa E) XIIa
C) Xa
200
The coagulation cascade is activated as part of the acute inflammatory response by means of: A) factor XIII B) factor VII C) factor VIII D) prekallikrein E) protein C
B) factor VII
200
Which of the following is not a complication of hypophosphatemia? A) muscle weakness B) respiratory depression C) hemolysis D) seizures E) rhabdomyolysis
D) seizures
200
Platelet microthrombus formation and vascular constriction occur in which of the zones of burn injury? A) zone of hyperemia B) zone of stasis C) zone of coagulation D) none of the above
B) zone of stasis
300
Which of the following motifs is important in steroid receptor structure? A) transmembrane domain B) zinc finger C) catalytic domain D) multiple C-terminal tyrosine residues E) SH2 domain
B) zinc finger
300
von Willebrand's disease (vWD) A) is the second most common bleeding disorder after vitamin K deficiency B) is caused by a quantitative or qualitative defect in a protein necessary for TF-VII interaction C) is inherited recessively in type I D) results in an elevated PT E) can be treated with cryoprecipitate
E) can be treated with cryoprecipitate
300
The initial compensatory mechanism of hypovolemic shock is the release of: A) aldosterone B) norepinephrine C) renin D) vasopressin E) angiotensinogen
B) norepinephrine
300
Which of the following medications is most likely to cause hyponatremia? A) furosemide B) thiazide diuretics C) lithium D) demeclocyline E) lovastatin
B) thiazide diuretics
300
Which of the following has not been implicated in the pathophysiology of frostbite? A) microemboli in the arteriolar system B) osmotic shifts in the intraextracellular interface C) intracellular ice crystals D) inhibition of the Na-K pump
D) inhibition of the Na-K pump
400
Which of the following is not a molecular motor protein? A) myosin B) kinesin C) dynein D) actin E) all of the above are molecular motor proteins
D) actin
400
Which of the following drugs is not known to affect platelet function? A) NSAIDS B) warfarin C) nitroprusside D) furosemide E) abciximab
B) warfarin
400
An example of an anti-inflammatory cytokine is: A) IL-2 B) IFN-gamma C) Lymphotoxin-alpha D) IL-4 E) TNF-alpha
D) IL-4
400
You admit a 69-year old man for resection of squamous cell carcinoma of the lung. Laboratories demonstrate a serum calcium level of 16. Which of the following will not lower the calcium level? A) gallium nitrate B) calcitonin C) furosemide D) HCTZ E) bisphosphonates
D) HCTZ
400
Critical factors in the "take" of a skin autograft include all of the following except: A) thickness of the graft B) presence of elastin fibers in the graft C) anatomosis of capillaries in the graft to capillaries in the bed D) diffusion of metabolites in the graft cells to plasma in the wound bed
B) presence of elastin fibers in the graft
500
A eukaryotic cell is lysed and fractionated into plasma membrane, cytosolic, and nuclear fractions. Which of the following hormones would most likely be found in the nuclear fraction of the cell? A) human chorionic gonadotrophin B) glucagon C) aldosterone D) gastrin E) histamine
C) aldosterone
500
Which of the following devices provides the least amount of adjacent tissue damage during normal usage? A) electrocautery on cutting mode B) electrocautery on coagulation mode C) harmonic scalpel D) argon beam coagulation E) Nd-YAG laser
C) harmonic scalpel
500
Inflation of the IABP occurs at which point on an ECG? A) T wave B) P wave C) PR interval D) R wave E) QRS complex
A) T wave
500
You are taking care of a man with bladder cancer who has undergone cystectomy with urinary drainage via an ileal conduit. Which of the following is not a complication of urinary diversions? A) metabolic acidosis B) urolithiasis C) cholelithiasis D) hyperkalemia E) adenocarcinoma
D) hyperkalemia
500
The site of injury in toxic epidermal necrolysis (TENS) and Stevens-Johnson syndrome (SJS) is: A) the Nikolsky body B) the basement membrane of the epithelium C) the dermoepidermal junction D) the endoplasmic reticulum
C) the dermoepidermal junction
M
e
n
u