Federal Regulations
What does the FDA stand for?
Food and Drug Administration
This demonstrates product quality via materials, components, and controlled spaces
Quality Control
These enzymes used in gene editing were originally evolved by bacteria to defend against viruses
Restriction Enzymes
Process by which bacteria intake foreign DNA from their environment
Transformation
Control
What is the purpose of a IND?
Facilities
2 DNA strands in a double helix move in which direction?
Antiparallel
5'3 or 3'5 direction
Bacteria can form bridges to share DNA via direct cell to cell contact.
What is the term used to refer to an experiment or research performed through artificial or computer test models?
In Silico
GFI (Guidance for Industry)
What laboratory device spins micro-volumes at high speed to separate components by density?
Microcentrifuge
What is the section of DNA where translation/replication of a gene is initiated?
promoter
Gel Electrophoresis primarily separates DNA fragments based on what?
Size, number of base pairs
This type of experimental trial involves both the researcher and subjects being unaware of who is receiving a treatment
Double Blind
After scientists in the 1970s were caught faking lab safety data, what rules were created to make sure lab test on animals are honest & reliable before any medicine can be tested in people?
What is the proper protocol for making a correction on an error in a formal laboratory notebook?
Cross through the mistake and initial
Which restriction enzyme shares an identical restriction site sequence with another restriction enzyme?
Isoschizomer
What does CRISPR stand for?
Clustered Regularly Interspaced Palindromic Repeats
This refers to a process where a scientific study is reviewed by other researchers and potentially repeated to ensure its validity before publication.
Peer Review
Which division of the FDA is responsible for regulating prescriptions, generic drugs, over-the-counter medications?
CDER
Center for Drug Evaluation and Research
Phase 4 clinical trials are primarily responsible for which types of studies?
Long term outcomes
The strand of DNA during replication that forms in small fragments in the 5'3 direction is known as what.
Lagging Strand
Transfection
A study that follows a large group of patients after administering a drug treatment to monitor effects would be considered what type of study? (3 Words)
Prospective Experimental Cohort