Ozempic
Semaglutide
Hypoglycemia is defined as blood glucose of less than this lab result
70 mg/dL
This has been the first-line pharmacotherapy agent of choice for years in Type 2 Diabetes
What is metformin
This side effect of metformin usually resolves with time and can also be managed with slow dose titration
What are GI-side effects
An A1c of this or greater can be used as a diagnostic of Type 2 Diabetes
What is A1c of 6.5%
Lantus
Insulin Glargine
These cells produce insulin within the pancreas
What are Beta cells
What is one class of drug that carries a significant risk of Hypoglycemia
Several classes including: Insulin, sulfonylureas, and meglitinides
Necrotizing fasciitis of the perineum can be associated with this class of drug
SGLT2-inhibitors
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Invokana
Canagliflozin
This is the mainstay of treatment for Type 2 Diabetes
Lifestyle changes
This class of medication is recommended for type 2 diabetic patients with Heart Failure according to the 2026 ADA guidelines
What are SGLT2-inhibitors
This drug has an increased risk of HF and fluid retention
What is pioglitazone
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Actos
Pioglitazone
This microvascular complication of diabetes is the leading cause of non-traumatic lower-limb amputations
What is diabetic peripheral neuropathy
What class of drugs should not be given together with GLP-1 receptor antagonists and why?
What are DPP4-inhibitors because they prevent the breakdown of endogenous GLP-1 resulting in duplicate therapy
Thyroid C-cell tumors have been identified in rodents; human relevance not determined, in this class of drug
What are GLP1-RAs
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Nateglinide
Starlix
Patients with a severe hyperglycemic state develop this condition despite having enough residual insulin secretion to prevent lipolysis
What is hyperosmolar hyperglycemic state
Alpha-glucosidase inhibitors work through this mechanism of action
What is competitively inhibiting enzymes that convert complex nonabsorbable carbohydrates into simple absorbable carbohydrates resulting in delayed carbohydrate absorption thus reducing the rise in postprandial blood glucose concentrations
This drug is not recommended in patients with previous or current bladder cancer
What is Pioglitazone
This character represents the 12th Arcana of the 22 major Arcana
What is the Hanged man