Brand/Generic
Pathophysiology
Pharmacology
Side Effects
Hope for the Best
1

Ozempic


Semaglutide


1

Hypoglycemia is defined as blood glucose of less than this lab result

70 mg/dL

1

This has been the first-line pharmacotherapy agent of choice for years in Type 2 Diabetes

What is metformin


1

This side effect of metformin usually resolves with time and can also be managed with slow dose titration

What are GI-side effects

1

An A1c of this or greater can be used as a diagnostic of Type 2 Diabetes

What is A1c of 6.5%

2

Lantus

Insulin Glargine

2

These cells produce insulin within the pancreas

What are Beta cells

2

What is one class of drug that carries a significant risk of Hypoglycemia

Several classes including: Insulin, sulfonylureas, and meglitinides

2

Necrotizing fasciitis of the perineum can be associated with this class of drug

SGLT2-inhibitors

2

Leave earlier 2 minutes

Leave earlier 2 minutes

3

Invokana

Canagliflozin

3

This is the mainstay of treatment for Type 2 Diabetes

Lifestyle changes

3

This class of medication is recommended for type 2 diabetic patients with Heart Failure according to the 2026 ADA guidelines

What are SGLT2-inhibitors

3

This drug has an increased risk of HF and fluid retention 

What is pioglitazone

3

Leave earlier 3 minutes

Leave earlier 3 minutes

5

Actos

Pioglitazone

5

This microvascular complication of diabetes is the leading cause of non-traumatic lower-limb amputations

What is diabetic peripheral neuropathy

5

What class of drugs should not be given together with GLP-1 receptor antagonists and why?

What are DPP4-inhibitors because they prevent the breakdown of endogenous GLP-1 resulting in duplicate therapy

5

Thyroid C-cell tumors have been identified in rodents; human relevance not determined, in this class of drug

What are GLP1-RAs

5

Stay 5 minutes longer

Stay 5 minutes longer

10

Nateglinide

Starlix

10

Patients with a severe hyperglycemic state develop this condition despite having enough residual insulin secretion to prevent lipolysis 

What is hyperosmolar hyperglycemic state

10

Alpha-glucosidase inhibitors work through this mechanism of action

What is competitively inhibiting enzymes that convert complex nonabsorbable carbohydrates into simple absorbable carbohydrates resulting in delayed carbohydrate absorption thus reducing the rise in postprandial blood glucose concentrations 

10

This drug is not recommended in patients with previous or current bladder cancer

What is Pioglitazone

10

This character represents the 12th Arcana of the 22 major Arcana

What is the Hanged man

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