The best tolerated statins in patients with muscle aches
pravastatin, rosuvastatin (Hydrophilic Statins)
A patient in the ED loses consciousness soon after arriving. He is unarousable, and radial pulses cannot be palpated. ECG is shown below. This is the next step in management.
Defibrillation
Among patients at high risk for cardiovascular events but without diabetes, targeting a systolic blood pressure of less than 120 mm Hg resulted in lower rates of fatal and nonfatal major cardiovascular events and death.
SPRINT
The Glomerulonephropathy most responsive to steroid therapy.
Minimal change disease
The PDE inhibitor used in treating PAD is contraindicated in this population.
Congestive Heart Failure

A 38-year-old presents to the emergency department for dyspnea and palpitations that started 45 minutes ago while they were tying their shoes. BP 125/78 mmHg, HR 180 bpm. EKG is shown. This is the next best step in management.
Vagal maneuvers
-Ask the patient to bear down
-Carotid massage
Catheter Ablation as treatment for atrial fibrillation in patients with Heart Failure.
CASTLE AF
First line antihypertensive in patients with CKD.
Thiazide diuretic.
Type of acid-base disorder caused by Topiramate
NAGMA- Type 2 RTA
Confirmatory diagnostic testing and treatment for cardiac amyloidosis.
TTR gene sequencing, Tafamidis
A 38-year-old man presents to the clinic for routine follow-up. He has no acute complaints, and his vital signs are normal. ECG reveals sinus rhythm with a heart rate of 80bpm and a corrected QT interval of 498. He states that his father passed at the age of 42, and his death was attributed to a heart problem. This is the best step in management
Beta blocker
Class 1 recommendation to initiate Angiotensin-Neprilysin inhibitor in patients with NYHA stage II-III HFrEF to improve morbidity and mortality.
PARADIGM HF
Indications for dialysis
Refractory acidemia
Refractory Hyperkalemia
Refractory Intoxication with Dialysable Substances
Refractory Volume overload
Uremia as evidenced by encephalopathy or pericarditis
A 42-year-old woman presents to the hospital with 3 days of nausea and vomiting and is found to have a small bowel obstruction. A nasogastric tube is placed and set to suction. Venous Blood gas collected on day 2 of admission is as follows: pH 7.49, PCO2 42, PaO2 49, HCO3 32.
This is the most appropriate treatment.
IV Normal saline
A 27-year-old male presents to the hospital with 2 weeks of weakness, chills, and high-grade fevers. He is found to have leukocytosis, and crackles are apparent on lung examination. EKG is shown above. This is the diagnosis and next step in management.
Perivalvular Abscess, surgical intervention
In this trial, the addition of acetazolamide to a loop diuretic improved the following acid-base disorder and shortened length of hospital stay.
ADVOR trial, Metabolic Alkalosis
A 40-year-old woman with a known history of Sjögren's disease and Type 1 RTA is evaluated for flank pain. This is the most likely diagnosis.
Medullary Nephrocalcinosis