ETIOLOGY
Which of the following viruses is most commonly associated with acute liver failure in children?
A. Hepatitis C
B. Hepatitis B
C. Hepatitis A
D. Hepatitis D
C. Hepatitis A
The typical incubation period for Hepatitis A is:
A. 2–7 days
B. 7–10 days
C. 15–40 days
D. 60–90 days
C. 15–40 days
Which marker appears first during acute Hepatitis B infection?
A. Anti-HBc IgM
B. HBsAg
C. Anti-HBs
D. HBeAg
B. HBsAg
Hepatitis A live attenuated vaccine is administered as:
A. Two doses at 0 and 6 months
B. Single dose at 12 months
C. Three doses at birth, 6, and 14 weeks
D. Booster every 5 years
B. Single dose at 12 months
Which metabolic disease is a cause of acute liver failure?
A. Phenylketonuria
B. Wilson disease
C. Cystic fibrosis
D. Maple syrup urine disease
B. Wilson disease
A patient with hepatitis A develops dark urine and pale stools during which phase?
A. Prodromal phase
B. Icteric phase
C. Convalescent phase
D. Chronic phase
B. Icteric phase
Detection of IgM anti-HAV indicates:
A. Chronic hepatitis A
B. Past HAV infection
C. Recent HAV infection
D. Vaccination
C. Recent HAV infection
What is the schedule for recombinant hepatitis B vaccination in infants?
A. 0, 6, and 12 months
B. Birth, 6, 10, and 14 weeks
C. Birth and 6 months
D. 2, 4, and 6 weeks
B. Birth, 6, 10, and 14 weeks
Which of the following is a recognized drug-induced cause of acute liver failure?
A. Amoxicillin
B. Ibuprofen
C. Acetaminophen overdose
D. Omeprazole
C. Acetaminophen overdose
Hepatitis E virus infection is especially severe in which population?
A. Neonates
B. Pregnant women
C. Elderly males
D. Patients with diabetes
B. Pregnant women
Which serological test confirms recent Hepatitis E virus infection?
A. IgG anti-HEV
B. HBsAg
C. IgM anti-HEV
D. Anti-HBc IgG
C. IgM anti-HEV
Which of the following indirectly prevents hepatitis D infection?
A. Hepatitis D vaccine
B. Hepatitis C vaccine
C. Hepatitis B vaccination
D. Antiviral prophylaxis
C. Hepatitis B vaccination
Gestational alloimmune liver disease is a cause of acute liver failure seen in:
A. Neonates
B. Adolescents
C. Pregnant women
D. Elderly males
A. Neonates
Which Viral hepatitis has extrahepatic manifestations polyarthritis nodosa and glomerulonephritis, skin lesions like urticarial rash?
A. Hepatitis A
B. Hepatitis B
C. Hepatitis C
D. Hepatitis E
B. Hepatitis B
The presence of anti-HBc IgG and absence of HBsAg indicate:
A. Acute infection
B. Chronic infection
C. Recovery from past HBV infection
D. No exposure
C. Recovery from past HBV infection
Post-exposure prophylaxis for Hepatitis A can be given using:
A. Interferon alpha
B. IgM anti-HAV
C. Immunoglobulin G within 2 weeks
D. Lamivudine
C. Immunoglobulin G within 2 weeks
Severe heart failure can lead to acute liver failure primarily due to:
A. Autoimmune reaction
B. Hepatic vascular occlusion
C. Drug toxicity
D. Viral reactivation
B. Hepatic vascular occlusion
Which vasculitis is often associated with hepatitis C virus in children?
A. Essential mixed cryoglobulinemia
B. Kawasaki disease
C. PAN
D. Takayasu arteritis
A. Essential mixed cryoglobulinemia
Which of the following tests is most sensitive for detecting HCV infection?
A. IgM anti-HCV
B. HCV-RNA PCR
C. Anti-HBs
D. Anti-HAV IgG
B. HCV-RNA PCR
A recombinant genotype 1 Hepatitis E vaccine has been licensed since 2011 in:
A. India
B. Japan
C. China
D. USA
C. China