Dendritic Cells
Only one of three cell types with this molecule for "presenting" fragments.
What is MHC-II?
This is the main "recognition molecule" in the plasma membrane of TH cells.
What is the T cell receptor (TCR)?
This is the main "recognition molecule" in the plasma membrane of TC cells.
What is a TCR?
This is the main "recognition molecule" on the surface of B cells.
What are antibodies?
The classical pathway of complement activation always starts with this complement component.
What is C1?
The molecule that "presents" fragments that is found on all the nucleated cells of the body, including dendritic cells.
What is MHC-I?
These cells always require the "help" of TH cells to be activated.
What are B cells?
These cells are the target of activated TC cells.
What are infected self cells?
This is what B cells become once they are activated.
What are plasma B cells?
The alternative pathway of complement activation always starts with this complement component.
What is C3?
The immune cells that can be activated by dendritic cells presenting fragments on MHC-I.
What are cytotoxic T cells (TC cells)?
This protein ensures that the TCR on TH cells only responds to fragments presented by MHC-II molecules.
What is CD4?
This protein ensures that the TCR on TC cells only responds to fragments presented by MHC-I molecules.
What is CD8?
This is what plasma B cells do.
What is secrete copious amounts of a single antibody?
This is what the MAC, which appears at the end of the complement activation pathway, does.
What is create a non-specific plasma membrane pore?
No matter what dendritic cells phagocytose, fragments of it are presented on these.
What are MHC-II molecules?
TH cells help activate these cells only when dendritic cells "cross-prime".
What are cytotoxic T cells (TC cells)?
This cell is always needed to activate a TC cell.
What is a dendritic cell?
A B cell is never activated without the participation of this cell.
What is a TH cell?
This is how the classical pathway ensures it only attacks pathogens.
When a dendritic cell phagocytoses a virus, fragments are presented here.
What are both MHC-I AND MHC-II molecules?
A TH cell recognition complex consists of all of these components.
what are CD4::MHC-II::fragment::TCR?
A TC cell recognition complex consists of all of these components.
What are CD8::MHC-I::fragment::TCR?
This is how dendritic cells can help B cells.
What is clonally expanding the right TH cell to activate the B cell?
This is how the alternative pathway ensures it only attacks pathogens.
What is C3b is inactivated by proteins in the plasma membrane of self cells?