Stimulants
Depressants
Psychedelics & Hallucinogens
The Brain on Drugs
Pop Culture & Fun Facts
100

This legal stimulant is found in coffee, tea, and energy drinks.

What is caffeine? 

100

This legal depressant is commonly consumed in social settings.

What is alcohol? 

100

This club drug, also called "Molly" or "X," has both stimulant and hallucinogenic effects. 

What is MDMA (Ecstasy)?

100

This brain chemical, known as the "feel-good" neurotransmitter, is heavily affected by drugs.

What is dopamine?

100

This legendary country singer, famous for Ring of Fire, overcame a long battle with amphetamine addiction.

Who is Johnny Cash?

200
This stimulant, commonly found in cigarettes, is one of the most addictive substances in the world.

What is nicotine?

200

This category of drugs includes Xanax and Valium, which are commonly prescribed for panic disorders or anxiety.

What are benzodiazepines? 

200
This hallucinogen, originally synthesized in 1938, is known for altering perception and causing visual distortions. 

What is LSD?

200

This brain imaging technique has shown lasting damage from drug use, even after stopping.

What is a brain scan (or fMRI/PET scan)?

200

This Friends actor wrote a memoir about his struggles with addiction and recovery before his passing in 2023. 

Who is Matthew Perry?

300

This stimulant drug is often prescribed for ADHD but can be abused.

What is amphetamine (e.g., Ritalin, Adderall)?

300

Mixing alcohol with other depressants can increase the risk of this life-threatening condition.

What is overdose or respiratory failure?

300

This dissociative anesthetic, often referred to as "angel dust," can cause severe disconnection from reality.

What is PCP?

300

Cocaine use affects this part of the brain primarily responsible for decision-making and executive functioning.

What is the prefrontal cortex? 

300

This stand-up comedian and actor, known for voicing Donkey in Shrek, was once arrested for drug possession before turning his life around.

Who is Eddie Murphy?

400

This highly addictive stimulant is often smoked in a crystalized form, leading to severe health consequences.

What is methamphetamine (or crystal meth)?

400

Withdrawal from this class of drugs can be life-threatening and requires medical supervision. 

What are sedatives? 

400

MDMA/Ecstasy made up of _____.

What is the combination of amphetamines and methamphetamine?

400

Long-term drug use can weaken this system in the brain, making stress harder to manage.

What is the limbic system? 

400

This musician, famous for songs like Purple Haze, was known for psychedelic drug use and had a major influence on rock music. 

Who is Jimi Hendrix? 

500

Chronic stimulant use can lead to this severe mental state, causing paranoia and hallucinations.

What is stimulant-induced psychosis? 

500

Depressants slow down this part of the body.

What is the central nervous system?

500

Surprisingly, this substance has traditionally been considered a hallucinogen among many scientific organizations.

What is marijuana?

500

This part of the brain, responsible for emotions (especially fear) and cravings, lights up when drug-related cues are seen.

What is the amygdala? 

500

This beverage was once made with small amounts of cocaine before the recipe was changed in 1929. 

What is Coca-Cola? 

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