Poliovirus enters the body through this opening.
Mouth
These were the only two countries reporting wild poliovirus type 1 cases in 2025.
Pakistan & Afghanistan
This virus causes polio.
Poliovirus
This group is at greatest risk of serious polio if exposed.
Unvaccinated people
Polio mainly affects this body system
Nervous System
In 2025, this country reported 31 WPV1 cases, the highest wild poliovirus count that year.
Pakistan
This type of poliovirus is naturally circulating and is different from vaccine-derived poliovirus.
Wild poliovirus / WPV
This environmental condition increases fecal-oral spread.
Poor Sanitation
After entering the body, poliovirus first multiplies mainly in this organ system.
Intestines/Gut
This entire continent was officially certified free of wild poliovirus in August 2020.
Africa
This abbreviation is used for wild poliovirus type 1.
WPV1
AFP stands for this.
Acute Flaccid Paralysis
Polio paralysis is often dangerous when it affects these muscles.
Breathing muscles
Pakistan and Afghanistan together reported this total number of WPV1 cases in 2025.
52 WPV1 cases
This term describes poliovirus that comes from the weakened vaccine virus in OPV after it has genetically changed during circulation.
VDPV / Vaccine-derived poliovirus
This sample is needed for confirming poliovirus infection in AFP cases.
Stool Sample
Paralysis in polio occurs because the virus damages these nerve cells.
Motor neurons / Anterior horn cells
This country had 66 cVDPV2 cases reported in 2025 in GPEI weekly country updates.
Nigeria
“Sabin virus” usually refers to the weakened poliovirus strains used in this vaccine.
OPV / Oral Polio Vaccine
Paralysis usually appears within this range after poliovirus infection.
7 to 21 days