What are the USPSTF criteria for annual lung‑cancer screening with low‑dose CT?
Adults age 50‑80 years with ≥20 pack‑year smoking history who currently smoke or quit within the past 15 years.
What is the maximum daily over‑the‑counter ibuprofen dose for adults?
1,200 mg.
How often should A1C be checked in a patient with well‑controlled diabetes?
Every 6 months.
What lab abnormality often precedes creatinine rise in rhabdomyolysis?
Elevated serum creatine kinase (CK).
As per Dr. Dominguez-Wiscovitch's case presentation, what are the first two steps in the diagnostic work up of a new thyroid nodule?
1. TSH
2. Thyroid Ultrasound
What is the target office blood pressure for most non‑pregnant adults according to the 2023 ACC/AHA guidelines?
<130/80 mmHg.
Which oral antihyperglycemic agent remains first‑line in overweight adults with type 2 diabetes unless contraindicated?
Metformin.
Lifestyle intervention aims for at least what percentage weight loss to improve glycemic control in type 2 diabetes?
≥5 % of baseline weight.
Elevated ferritin with transferrin saturation <20 % suggests what diagnosis?
Anemia of chronic disease / inflammation.
As per Dr. Kalish’s presentation, if a mixing study does NOT correct a patient’s elevated INR, what should be considered?
Presence of an inhibitor
Through which age should catch‑up HPV vaccination be routinely offered if not previously immunized?
Through age 26.
What is the standard adult dose of oseltamivir for influenza treatment in normal renal function?
75 mg orally twice daily for 5 days.
How frequently should blood pressure be screened in adults with previously normal readings (<120/80 mmHg)?
At least every 3 years.
Stool calprotectin is a non‑invasive marker used to help differentiate what condition?
Inflammatory bowel disease from IBS.
As per Dr. Fried's case presentation, ocular syphilis can occur at what stage of disease?
It can occur at ANY stage
Can affect any part of the eye (pan-ophthalmic).
Most common: posterior uveitis and panuveitis.
Others: optic neuritis, interstitial keratitis, retinal vasculitis, neuroretinitis.
At what age does the USPSTF now recommend beginning average‑risk colorectal‑cancer screening?
45 years.
Which inhaler class is recommended as initial maintenance therapy for COPD Group B (symptomatic, low exacerbation risk)?
LAMA + LABA dual therapy.
Name one alarm symptom prompting endoscopy.
dysphagia, odynophagia, unintentional weight loss, gastrointestinal bleeding (including hematemesis or melena), persistent vomiting, and unexplained iron deficiency anemia.
What condition causes an unreliable LDL calculation?
Hypertriglyceridemia causes an unreliable low-density lipoprotein LDL calculation, particularly when using the Friedewald formula.
The Friedewald equation assumes a fixed ratio of triglycerides to very low-density lipoprotein cholesterol (VLDL-C), which becomes inaccurate as triglyceride levels rise, especially above 150 mg/dL (1.7 mmol/L), and is considered invalid when triglycerides exceed 400 mg/dL (4.5 mmol/L)
As per Dr. Peng’s talk, Apo B is NOT found on these two components of cholesterol
HDL and chylomicrons
Patients with chronic GERD and multiple risk factors (including age >50, tobacco smoking & obesity) should start Barrett’s esophagus screening endoscopy at what age?
50 years old
Which common cholesterol medication must be stopped before dispensing nirmatrelvir/ritonavir (Paxlovid) because of serious interaction?
Simvastatin (and lovastatin).
Paxlovid is a potent inhibitor of CYP3A4 via the ritonavir component, which can cause a marked increase in simvastatin plasma concentrations. This interaction significantly elevates the risk of myopathy and potentially life-threatening rhabdomyolysis.
Beers Criteria advise avoiding which antihistamine?
Diphenhydramine.
Low albumin with normal transaminases suggests what chronic issue?
Cirrhosis
Also nephrotic syndrome, protein-losing enteropathy
As per Dr. Gandhi's R2 talk, the SELECT trial studied semaglutide vs placebo in what population?
In overweight/obese patients with established CVD (MI, stroke, PAD) without diabetes
First trial to show CV risk reduction with a GLP-1 RA in overweight/obese patients without diabetes