Naming
You have glycine and lysine. If a dipeptide is formed, what is its name?
Gly-Lys
For an amide reaction, name the biproduct
Water
In basic conditions, What is the overall charge of glutamate?
+
Name all the different types of reactions that amino acids can undergo
oxidation (Cystine-Cysteine), Amide formation (between amino acids), and acid base reactions (between themselves and with the environment)
I have two Cysteine residues. How would I form a covenant bond between each residue's sulfur?
oxidation reaction
Lets say I have 5 amino acids. Does the order I form them into a poly peptide matter? Explain
Yes it matters. Since each amino acid has specific properties. Different orders or peptides lead to polypeptides with different properties
Fully draw out the following tripeptide: Phe-Pro-Gly
See board
I have Proline. I want it to have a negative charge overall. What conditions would I subject it to?
Basic Conditions
If I perform an oxidation reaction of two cysteine molecules. Is this process reversible? Explain your answer
A reduction can break the S-S covenant bond between the cysteine side chains. Reducing agent is needed
Lets say I have Asp-His. What reaction would I perform to break up this dipeptide into Asp and His
Amide Hydrolysis
If I have Leu-Ser, and I want to make the net charge of the whole dipeptide positive, what conditions would I subject it to?
Basic conditions
For Lysine, Phenylalanine, Proline, and Glycine, determine for each whether or not the alpha carbon is chiral or not
Glycine is the only amino acid that is achiral (alpha carbon is bound to two hydrogens)