True or False: Take missed doses as soon as possible within 12 hrs of missed dose
True
Avoid grapefruit products
What is Drug-Food Interaction?
True or False: Does amlodipine cause flushing?
True
24 hours
What is the duration?
True or False: this medication cures hypertension
False - this medication controls hypertension but does not cure it
The inhibition of which enzyme causes amlodipine to increase in the blood
CYP3A4
What are some side effects of amlodipine?
dizziness, fatigue, gingival hyperplasia, nausea
64-90%
What is the absorption?
True or False: Caution patient to stay in the same position to minimize orthostatic hypotension
False - caution patient to SLOWLY switch positions to minimize orthostatic hypotension
Do not exceed 20mg of this drug a day
What is Simvastatin?
What are symptoms of a heart attack?
Chest/jaw/left arm pain, shortness of breath, unusual sweating
Probably crosses the placenta
What is the distribution?
True or False: Amlodipine tablets can be crushed and mixed into food
True - the dose may be crushed and mixed into a small amount of soft food, such as applesauce or yogurt
What side effect occurs when used with fentanyl?
Hypotension
Gingival hyperplasia, nausea
What are gastrointestinal side effects?
6-9 hours
What is the peak?
True or False: During pregnancy the safety of amlodipine has been proven
False - During pregnancy the safety of amlodipine has not been proven. Amlodipine is therefore considered a pregnancy category C drug. Use amlodipine only if the potential benefit justifies the potential risk
What is the concurrent use of NSAIDs
May decrease effect of antihypertensives
What are 2 cardiovascular side effects?
peripheral edema, angina, bradycardia, hypotension, palpitations
Increased in geriatric patients & hepatic impairment
What is the Half-Life?