Cells
Skin
Bones
Skin part 2
Bones part 2
100

 Power plant of the cell

Mitochondria

100

Found in thick skin only

Lucidum layer


100

this cartilage is found in the ears and nose 

elastic cartilage 
100

Functions of the Integument

The- Temp reg.

Money- metabolic functioning (creates vit D and collagen); conversion of carcinogens and activate some hormones.

Cant or CAN*- cutaneous sensation (touch/senses)

Buy- blood reservoir (RBC in bone marrow) 5% blood vol

Everything- excretion (waste products: sweat)

People- protection (external environment)



100

last step of bone repair 

bone remodeling

200

Tough, insoluble, ropelike protein fibers

Intermediate Filaments

200

Fear =

Liver issues=

Lack of oxygen=

Fear= Pallor

Liver Issues= Jaundice

Lack of Oxygen= Cyanosis

200

the vertebrae are part of the axial or appendicular skeleton?

axial skeleton

200

Difference between the three types of burns.

-Appearance, and Integumentary Damage

First degree: Partial-thickness burns; Epidermal damage only

– Localized redness, edema (swelling), and pain

Second degree: Epidermal and upper dermal damage

– Blisters appear

Third degree: Full-thickness burns 

-Skin gray-white, cherry red, or blackened

-Not painful (nerve endings destroyed) or swollen


200
PTH increases or decreases blood calcium levels?

increases blood calcium levels

300
List 3 differences between Smooth/Rough ER

ROUGH:

  • ALL secreted proteins

  • Proteins bind to transport to Golgi A.

  • synthesizes phospholipids.

  • HAS RIBSOMES

SMOOTH

FREE of ribosomes

-Site of lipid and cholesterol synthesis

-Lipid metabolism (Fats) & Transports Fats

-Drug detoxification

-Calcium Storage and release

-Glycogen to free glucose

300

List the 5 layers on skin from superficial to deep

TOP (superficial)

C- Can’t (corneum)

L-Let (lucidum)

your

G-Grandma (granulosum)

S-Steal (spinosum)

your

B-Boyfriend (Basale)

BOTTOM (deep)

300
this is the part of the bone where the majority of the growth occurs 

epiphyseal line 

300

List the MAJOR differences between types of cancer.

Basal Cell carcinoma: LEAST Malignant; MOST common

Squamous Cell: Second most common, METASTASIZES, prognosis not terrible

Melanoma: DEATH, Metastasizes & Resistant to Chemo, WORST PROGNOSIS

300

these are small cavities that contain osteocytes

lacunae 

400

Explain Difference between Peroxisomes and Lysozymes

Peroxisomes: Consist of Oxidases (converts Hydrogen peroxide HCO3… still toxic) and Catalases (converts H2O to O2) to detoxify harmful/toxic substances

Lysozymes: Membranous bags of acidic (H ions) hydrolytic digestive enzymes that eat bacteria/viruses/toxins and dispose of them, degrade non-functional organelles/dead cells, autolysis, and metabolic functions causing break down and release of glycogen, and breaking down bone to release calcium

400

List 3 characteristics of Basale Layer

-DEEP… attach to dermis

-” stratum germinativum” .... Germs in basement

-ROW OF STEM CELLS (miotic)... active cells with organs (25-45 days to die and move up surface)

***MELANOCYTES MAJORITY HERE (UV ray protection)... being all the way in basement means complete darkness and protection from all lights

400

in this type of bone growth, the bones are getting longer

interstitial growth

400

Early detection of Melanoma/Skin Cancers...

-A: asymmetry; the two sides of the pigmented area do not match

– B: border irregularity; exhibits indentations

– C: color; contains several (black, brown, tan, sometimes red or blue)

– D: diameter; larger than 6 mm (size of pencil eraser)

-E: Evolution: How has it changed?

400

Bone develops from fibrous membrane: is this endochondral or intramembranous ossification

intramembranous ossification

500

Explain how proteins are synthesized in the Golgi Apparatus (in order)

Vesicles from Rough ER→ G.A.-->Cis face: modifies, tags, sorts, and packages proteins→ trans face: ships proteins out the cell (three types: secretory (proteins), membrane (lipids/transmembrane), and digestive enzymes (lysozymes)

500

List 3 Functions of the Corneum layer

-- Protect deeper cells from environment and water loss

– Protect from abrasion and penetration

– Barrier against biological, chemical, and physical assaults

500
this type of ossification forms most of the skeleton

endochondral ossification

500

Difference between eccrine and apocrine glands

Merocrine or Eccrine:

-DUCTS connect to pores

Function? Thermoregulation (SNS… SWEAT)*know what they secrete

Apocrine: 

-Ducts EMPTY into hair follicles (LARGER)

FUnction? Sweat + Fatty sub + proteins (body odor, and milky yellowish gland)

FUNCTIONS OF SEBUM, Ceruminous glands, modified apocrine glands, secretions in sweat

500
when there is low blood calcium, is it osteoclasts or osteoblasts that are activated
osteoclasts
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