Lymph Flow
sequence of lymph flow in order
•Interstitial fluid → capillaries → vessels → trunks → ducts → veins
2 types of innate immunity
surface barriers + internal defenses
what are the 2 types of adaptive immunity
cell mediated + antibody mediated
what does interleukin-1 do?
Stimulates T cell proliferation
What is the most abundant antibody?
IgG
what duct drains most of the body?
Thoracic duct
main chemical defense in stomach?
gastric juice
what do T cells recognize?
processed antigen fragments
What does interleukin-6 do?
enhances b cell differentiation
What is the first antibody produced
IgM
The R lymphatic duct drains what?
Right upper extremities above the diaphragm
function of Nk cells?
destroy infected cells by perforating membrane
what do B cells recognize?
free antigens in fluids
Function of cytotoxic T cells?
Kill infected cells
Where is IgA found?
Mucus, saliva, tears
what process creates lymph fluid from interstitial fluid?
osmotic diffusion
steps of phagocytosis in order
chemotaxis, adherence, ingestion, digestion, killing
define immunogenicity
ability to provoke immune response
What is the difference between granzymes vs perforin?
Granzymes= causes apoptosis of infected cell
Granzymes+ perforin= causes cytolysis of infected body cell
What is the function of IgE?
Allergic and hypersensitivity reactions
why is the lymph flow slow?
Low pressure; relies on skeletal muscle
what does the complement system do?
cytolysis, inflammation, enhances phagocytosis
define epitopes
small antigen regions recognized by immune system
What do interferons do?
Inhibits viral replication
Why does igG rise faster during second exposure
Memory cells