Sliding Filament Theory
Where is myosin found in skeletal muscle cells?
Thick filaments
What stimulus do you need to reach before depolarization?
Threshold
Where is the calcium stored during muscle relaxation?
Sarcoplasmic Reticulum
What is the function of tropomyosin?
Blocks the binding between actin and myosin
How many sodium and potassium ions are there and which direction do they move?
3 Na Out, 2 K In
TN-TM complex blocks cross-bridge bind sites on which filament?
Thin filament
Actin is a binding site for?
Myosin
What happens during hyperpolarization?
K+ channels remain open and Na channels are resetting
What is excited at the motor end plate during contraction?
Sarcolemma
Name one of the roles of ATP in the sliding filament theory?
Forms cross bridge, disconnects myosin from binding site, and transports calcium ions to the SR
Explain refractory period
It ensures one-way direction of action potentials through absolute and relative periods
What is required for the myosin heads to detach from the thin myofilaments?
ATP
Myosin, actin, tropomyosin, troponin, calcium, and ATP
What is this principle? "If threshold stimulus is applied, AP is conducted along entire axon at constant and max strength (independent of stimulus intensity)."
All or none principle
What destroys Ach on the motor end plates?
Acetylcholinesterase