History of ID
Debunking the myth: PCN allergies
Name that bug!
Name that drug!
Dr. Who or new antibiotic?
100
Alexander Fleming discovered this antibiotic when he noticed that a fungus had contaminated a culture plate of Staphylococcus bacteria he had accidentally left uncovered. The fungus had created a bacteria-free zone where it grew on the plate.
What is penicillin?
100
This is the percent of the US population that reports a penicillin allergy.
What is 10%?
100
This is the only real indication for oral vancomycin.
What is C.difficile?
100
A red, diffuse rash can appear on the trunk of patients receiving a rapid infusion of this antibiotic.
What is vancomycin?
100
PRALIX
What is Dr. Who?
Pralix is a psychic who helped the Fourth Doctor defeat The Captain.
200
This rare and deadly disease first discovered in 1976 near a river in what is now the Democratic Republic of Congo spreads through direct contact with bodily fluids and causes fever, weakness, diarrhea, and unexplained hemorrhage.
What is Ebola?
200
This commonly used cephalosporin does not share any R groups with any other beta lactam and is generally considered safe to use in patients with a reported penicillin allergy.
What is cefazolin?
200
A toxic patient with a spreading rash? Better order ceftriaxone STAT to cover this bug.
What is Neisseria meningitidis?
200
What’s that you say? This antibiotic with Gram-negative coverage can cause ototoxicity.
What is gentamicin (or other aminoglycoside)?
200
FETROJA
What is new antibiotic?
Cefidericol (Fetroja) is a new antibotic approved for the treatment of infections due to carbapenemase producing Gram-negative organisms.
300
This infectious disease caused by one of two virus variants, Variola major and Variola minor, achieved global eradication in 1980.
What is smallpox?
300
In a study performed in the emergency room at Children’s Wisconsin and named one of the top ten publications in Pediatrics in 2017, ____ out of 100 children with a reported penicillin allergy who underwent three tier penicillin allergy testing had a true allergic reaction.
What is ZERO?
300
This bug is frequently encountered in upper respiratory tract infections and “typically” treated with azithromycin.
What is Mycoplasma pneumoniae?
300
Administering an SSRI with this antibiotic can put patients at risk for serotonin syndrome.
What is linezolid?
300
RECARBRIO
What is new antibiotic?
Imipenem/cilistatin/relebactam (Recarbrio) is a new antibiotic approved for the treatment of complicated intra-abdominal and urinary tract infections caused by resistant Gram-negative organisms.
400
This antibiotic was first isolated in 1953 by Edmun Kornfeld (working at Eli Lilly) from a soil sample collected from the interior jungles of Borneo and was initially referred to as “Mississippi Mud”.
What is vancomycin?
400
This is the number of years at which approximately 80% of patients with an IgE-mediated penicillin allergy lose their sensitivity.
What is 5-10?
400
Unlike other carbapenem antibiotics, this Gram-negative organism is not covered by ertapenem.
What is Pseudomonas?
400
Treating anaerobes? This antibiotic can leave a bad taste in your mouth.
What is metronidazole?
400
DAVROS
What is Dr. Who?
Davros is a major enemy of The Doctor. He is a genius, but also a megalomaniac who believes he can become the supreme being and ruler of the Universe.
500
Albert Alexander was the first patient to be treated with penicillin in 1941. However, due to war-time restrictions, there was only a small quantity available. Doctors extracted penicillin from this body fluid to re-administer to the patient, but by the fifth day the drug ran out and he expired.
What is urine?
500
Broad spectrum antibiotics are often used as alternatives to penicillins in patients with a reported penicillin allergy and are associated with these negative outcomes (name 1).
What is higher health care costs?
What is increased risk for antibiotic resistance?
What is increased risk for adverse reactions?
What is treatment failure?
500
This inherently resistant Gram-negative organism, which is a common contaminant in patients with a trach/vent who have been exposed to broad spectrum antibiotics, is best treated with sulfamethoxazole/trimethoprim.
What is Stenotrophomonas maltophilia?
500
This antibiotic can cause a breakdown of muscle fibers resulting in severe pain. Monitoring of CK values before and during treatment is recommended.
What is daptomycin?
500
XENLATA
What is new antibiotic?
Lefamulin (Xenlata) is a new antibiotic approved for the treatment of community-acquired pneumonia.