Kinds of Antibiotics
How many different ways can antibiotics inhibit microbes?
four
What are the two methods of antibiotic resistance?
intrinsic and acquired
What was Salvarsan, one of the first antibiotics, active against?
Syphillus
What kind of mutation is happening in Gonorrhea for it to be resistant to ciprofloxacin?
point mutation
What are Dr. Humphrey's dogs names?
Luke and Leia
What kind of drugs can inhibit the cell wall of the diseases?
beta-lactam, cephalosporins, bacitracin, or vancomycin will be accepted
How do intrinsic methods cause resistance?
has to do with the structure (prevent entry, pump drug back out, lack target)
What was the original kind of penecillin?
benzylpenicillin or penicillian D
What kind of test did they use on the remnant N. gonorrhoeae-positive nucleic acid amplification test specimens?
PCR
What was on Dr. Humphrey's shirt for Halloween?
A yellow duck
What is an example of a kind of antibiotic that disrupts the cell membrane?
polymyxins
How do acquired methods stop antibiotics from working?
mutation, enzyme to attack drugs, or use alternative biochemical pathway
What detrimental side affects can aminoglycosides have?
kidney or auditory nerve problems
What individuals were excluded from the study?
Anyone who received antibiotics in the last 30 days
What are Dr Humphrey's TA's names?
Abby, Ny, and Nicole
What is the category of antibiotics that is generally called broad spectrum antibiotics?
Interference with protein synthesis
Why do you have to take all of the course of antibiotics prescribed to you?
so you kill all bacteria left in your system
What is the -cillin drug that was made to adjust the drug for better absorption?
amoxicillin
What was a limitation of the study?
small sample size and the subjects had to be in a symptomless phase of gonorrhea
What living creatures, other than dogs and germs, are featured a lot on Dr Humphreys' Instagram?
Shrimps and/or snails
How do doctors prescribe certain beta-lactam antibiotics to avoid resistance?
Prescribe two at once
What is the kind of resistance testing we did in lab this year?
Kirby-Bauer
What is the drug that is comparable to penicillin that is prescribed when the individual has an allergy to penicillin?
cephalosporin
How many participants were in the study?
117
What sexually transmitted disease does Dr Humphreys study?
chancroid!