This 4th generation drug has coverage against Pseudomonas
What is Cefepime
This PO drug with MRSA coverage cannot be used in pregnant women
What is TMP-SMX/Bactrim
What is Doxycycline
Women being treated with the 1st line choice for BV cannot do this on the weekend.
Drink alcohol 2/2 disulfiram reaction
A commonly used sulfa drug has this potentially severe adverse dermatologic manifestation
SJS-TEN
This antibiotic has the broadest coverage of the respiratory fluoroquinolones.
Bonus: which bugs do they cover better?
What is Moxifloxacin
Bonus: anaerobes, MSSA, strep pneumo
The drug most often used prior to surgery belongs to this generation of cephalosporins
What is 1st generation
What is Clindamycin
By adding this to amoxicillin, antibiotic coverage can be extended via this MOA.
Clavulanate/clavulanic acid
destruction of beta lactamase
This ototoxic, nephrotoxic and neurotoxic drug is commonly used for which obstetric complication?
Chorioamnionitis/Endometritis
Patients with confirmed atypical infections can be transitioned to these PO drugs.
NB: assuming sensitive
Azithromycin, Doxycycline, Moxifloxacin
This cephalosporin is used in newborns (<30 days) in treating Meningitis to avoid hyperbilirubinemia
Cefotaxime
The most commonly used IV anti-MRSA agent has this mechanism of action
Inhibits cell wall peptidoglycan formation (bactericidal)
This antibiotic can be used to treat both Actinomyces and Clostridium perfringens
Penicillin
Macrolides, Fluoroquinolones and Anti-malarial drugs should not be used in patients with this finding.
Patients with confirmed Pseudomonas infections can be transitioned to these PO drugs.
NB: assuming pan-sensitive
Ciprofloxacin, Levofloxacin
This cephalosporin has the longest serum half-life within its generation
What is Ceftriaxone (CTX)?
This anti-MRSA agent should not be used in patients also taking SSRIs
What is Linezolid
Bonus: why? Serotonin Syndrome
Zosyn has similar coverage to Unasyn in addition to these three bugs.
What are Pseudomonas, Citrobacter and Enterobacter
These drugs can increase the risk of pyloric stenosis in kids
Macrolides (Azithromycin, Erythromycin)
Patients with confirmed MRSA infections can be transitioned to the PO drugs
NB: assuming sensitive
TMP-SMX, Doxycycline, Clindamycin, Linezolid
I am the only cephalosporin with MRSA coverage
Hint: not often used clinically
What is Ceftaroline
This drug can be used for MRSA skin infections but is ineffective for Pneumonia due to this MOA.
Daptomycin
Binds to and is inactivated by surfactant
This drug is added to carbapenems to prevent inactivation in the renal tubules
What is cilastatin
This inexpensive, rarely-used medication can cause gray baby syndrome in premature infants
Chloramphenicol
This antibiotic regimen is sued for patients with fulminant C dif infection
Bonus: dosing
PO Vanc + IV metronidazole
Bonus: PO Vanc 500mg Q6H + IV Flagyl 500mg Q8H