Gen Z vs Millennial
MRSA is the Worsa
No O2
Oops, I did it again!
PO vs IV
100

This 4th generation drug has coverage against Pseudomonas

What is Cefepime

100

This PO drug with MRSA coverage cannot be used in pregnant women

What is TMP-SMX/Bactrim


What is Doxycycline

100

Women being treated with the 1st line choice for BV cannot do this on the weekend.

Drink alcohol 2/2 disulfiram reaction

100

A commonly used sulfa drug has this potentially severe adverse dermatologic manifestation

SJS-TEN

100

This antibiotic has the broadest coverage of the respiratory fluoroquinolones.

Bonus: which bugs do they cover better?

What is Moxifloxacin

Bonus: anaerobes, MSSA, strep pneumo

200

The drug most often used prior to surgery belongs to this generation of cephalosporins

What is 1st generation

200
This drug can be used to treat MRSA cellulitis as well as Gardnerella vaginitis

What is Clindamycin

200

By adding this to amoxicillin, antibiotic coverage can be extended via this MOA.

Clavulanate/clavulanic acid

destruction of beta lactamase

200

This ototoxic, nephrotoxic and neurotoxic drug is commonly used for which obstetric complication?

Chorioamnionitis/Endometritis

200

Patients with confirmed atypical infections can be transitioned to these PO drugs.

NB: assuming sensitive

Azithromycin, Doxycycline, Moxifloxacin

300

This cephalosporin is used in newborns (<30 days) in treating Meningitis to avoid hyperbilirubinemia

Cefotaxime

300

The most commonly used IV anti-MRSA agent has this mechanism of action

Inhibits cell wall peptidoglycan formation (bactericidal)

300

This antibiotic can be used to treat both Actinomyces and Clostridium perfringens

Penicillin

300

Macrolides, Fluoroquinolones and Anti-malarial drugs should not be used in patients with this finding.

Prolonged QT
300

Patients with confirmed Pseudomonas infections can be transitioned to these PO drugs.

NB: assuming pan-sensitive

Ciprofloxacin, Levofloxacin

400

This cephalosporin has the longest serum half-life within its generation

What is Ceftriaxone (CTX)?

400

This anti-MRSA agent should not be used in patients also taking SSRIs

What is Linezolid

Bonus: why? Serotonin Syndrome

400

Zosyn has similar coverage to Unasyn in addition to these three bugs.

What are Pseudomonas, Citrobacter and Enterobacter

400

These drugs can increase the risk of pyloric stenosis in kids

Macrolides (Azithromycin, Erythromycin)

400

Patients with confirmed MRSA infections can be transitioned to the PO drugs

NB: assuming sensitive

TMP-SMX, Doxycycline, Clindamycin, Linezolid

500

I am the only cephalosporin with MRSA coverage

Hint: not often used clinically

What is Ceftaroline

500

This drug can be used for MRSA skin infections but is ineffective for Pneumonia due to this MOA.

Daptomycin

Binds to and is inactivated by surfactant

500

This drug is added to carbapenems to prevent inactivation in the renal tubules

What is cilastatin

500

This inexpensive, rarely-used medication can cause gray baby syndrome in premature infants

Chloramphenicol

500

This antibiotic regimen is sued for patients with fulminant C dif infection

Bonus: dosing

PO Vanc + IV metronidazole

Bonus: PO Vanc 500mg Q6H + IV Flagyl 500mg Q8H

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