INR-terpret This!
Warfarin Wizardry
DOAC or DO-Not?
Heparin Headaches
Bleed or No Bleed?
100

This INR value is considered therapeutic for most patients treated for Afib or DVT/PE

What is INR 2-3? 

100

This common antibiotic that only is given for 3 day duration causes a major INR increase and requires warfarin holding

What is Bactrim?

100

This DOAC is the only one with a capsule that cannot be opened

What is dabigatran?

100

This is the test used to measure heparin efficacy

What is PTT?

100

This reversal agent is given in two separate doses inpatient for dabigatran 

What is Praxbind

200
If a patient's INR is 1.3 and Memorial Day barbecue just occurred, this is the likely cause 

What is increased Vit K intake?

200

This supplement lowers warfarin levels

What is St Johns Wort or saw palmetto? 
200

This DOAC is preferred in patients with CrCL< 30

What is Eliquis

200

This is the first step when HIT is suspected

What is Stop all heparin

200

This is the reversal agent for unfractionated heparin

What is protamine?

300

Patient has just started amiodarone and this interaction with the CYP enzyme will affect the INR.

What is CYP inhibition?

300

This organ is responsible for producing clotting factors

What is the liver 

300

This DOAC must be taken with food at doses >15 mg

What is Xarelto?

300

This is the typical onset window for HIT after starting heparin

What is Days 5-10?

300

This reversal agent is used when Andexxa is unavailable and is also used for warfarin reversals with Vitamin K

What is 4-Factor PCC?

400

This reversal agent is given orally if an INR is above 8.0, especially if patient has bleeding.

Vitamin K 

400

This common OTC pain reliever increases bleeding risk but does not change INR

What is ibuprofen? 

400

This drug is the specific reversal agent for Eliquis and Xarelto

What is Andexxa?

400

This type of heparin has the highest HIT risk

What is unfractioned heparin

400

This form of Vitamin K is not recommended due to its poor absorption

What is subcutaneous

500

This INR goal is a new development in guidelines for patients with mechanical aortic On-X valve?

What is INR goal 1.5-2.0? 

500

This genetic variant makes patients more sensitive to warfarin

What is VKORC1 or CYP2C9

500

This DOAC is not recommended if CrCL > 95

What is edoxaban

500

This lab monitoring used for patients on chronic Enoxaparin therapy is increasingly necessary for those who have renal issues or are pregnant

What is Anti-XA monitoring?

500

This DOAC has the highest GI bleeding risk

What is Xarelto 

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