Vitamin C
Name 3 sources of vitamin C.
Any of the following: citrus fruits, broccoli, strawberries, spinach, fortified foods, and supplements.
what is an antioxidant?
is a substance that inhibits oxidation and helps prevent damage caused by free radicals.
What is type 2 diabetes?
Type 2 Diabetes is a chronic metabolic disorder characterized by high blood sugar levels due to insulin resistance and beta-cell dysfunction.
What is secreted by endothelial cells to control vasodilation?
Nitric Oxide
True or False: Tumor cells can not adapt to high reactive oxygen species.
False
why can vitamin C be excreted in excess?
it is a water-soluble vitamin
what does an antioxidant do to a free radical?
neutralizes it, by donating electrons
what is it called when there is higher urinary excretion of Vitamin C in diabetic patients?
diabetic nephropathy
What is the main role of carnitine in the body?
Fatty acid shuttle to the mitochondria matrix.
Name one of the more holistic treatments for oxidative stress imbalances in cancer.
Antioxidants or Pro-oxidant
Is vitamin C and electron donor or acceptor?
Donor
which cells are more susceptible to oxidative damage in type 2 diabetes patients?
pancreatic beta cells
What happens to blood vessels without the presence of nitric oxide?
They will lose their ability to vasodilate and will become stiff.
Name three of the benefits of IV Vitamin C therapy.
Reduced pain, inflammation, fatigue, and side effects of chemo
what is the reduced form of vitamin C?
ascorbate
what is the recommended supplementation amount for Vitamin C in type 2 diabetes patients?
500-1000 mg
In what two ways does vitamin C act as an antioxidant to prevent plaque formation?
Prevents destruction of endothelial cells and prevents oxidation of LDL cholesterol.
Which doctors started the research of high-dose vitamin C therapy in the 1970s?
Dr. Linus and Dr. Ewan
what is vitamin C's role in collagen synthesis?
oxygenase uses iron as a cofactor but is needed in its ferrous form which requires ascorbate to act as a reducing agent.
what does adequate vitamin C intake promote the production of for good vascular health?
nitric oxide
What reacts to LDL cholesterol within the arteries when it has not been neutralized? (be specific with the name)
Reactive Oxygen Species (ROS)
What condition should be monitored closely when doing high-dose vitamin C therapy?
Kidney Disease Patients