Side Effects
What side effect is most common with 1st generation anti-psychotics
EPS
Schizophrenia
what is the generic name?
haliperidol
What is the generic name
Quetiapine
What is the most severe side effect of anti-psychotics you need to monitor for?
Neuroleptic Malignant Syndrome (NMS)
What EPS symptoms are present?
acute dystonia
akathisia
pseudoparkinsonism
What side effects are common?
Metabolic syndrome
Cataracts
QT prolongation
Dry mouth
Urinary retention
Constipation
Blurred vision/dry eyes
Sexual dysfunction
What level should you monitor in a patient on anti-psychotics?
prolactin
Low seizure threshold
Monitor prolactin levels
Monitor cardiac symptoms
what should be closely monitored?
monitor weight
monitor eyesight
monitor cardiac sx.
What is tardive dyskinesia?
repetitive motions of the face/neck/arms
What does decreasing Dopamine do for your patient?
Decreases delusions and hallucinations
What should you consistently monitor for patients Haldol?
weight
vital signs
cardiac function
prolactin (again)
what nursing implications are associated?
low seizure threshold
monitor weight
what does EPS stand for?
ExtraPyramidal Symptoms
What is the difference between 1st and 2nd generation antipsychotics?
If they act on serotonin in addition to dopamine
What ethnopharmacologic considerations are necessary?
Reduced activity in the Japanese population
Higher inducibility in Caucasians
Poor metabolism in Caucasians
Reduced function in Asian, Pacific Islander, African, and African American populations
Poor metabolism in Caucasians
Reduced function in Asian, Pacific Islander, African, and African American populations