Associated with neural tube defects when given in the first trimester of pregnancy.
What is EFV?
100
HLA-B*5701 is required prior to initiating this ARV.
What is abacavir?
100
These integrase inhibitors is co-formulated into a once daily tablet.
What is Elvitegravir (Stribild) and Dolutegravir (Triumeq)?
100
This class has the highest genetic barrier to drug resistance.
What is protease inhibitors?
200
Tablet=room temperature, solution=fridge
What is LPV/r? (oral solution 42% alcohol)
200
The amount of calories a patient is required to eat with Complera.
What is 400 kcal?
200
These NRTIs also have activity against Hep B.
What is TDF, 3TC, and FTC?
200
This integrase inhibitor should be administered with food.
What is elivtegravir?
200
Three potential barriers to ART adherence.
What is psychosocial issues, low health literacy, busy schedule, nondisclosure of status, access to medications, lack of insurance coverage, and lack of support?
300
These two PIs are associated with increased risk of kidney stones/cholethiasis.
What is atazanavir and indinavir?
300
Patients with an HVL >100,000 are more likely to fail with this NNRTI.
What is rilpivirine (Complera)?
300
Lactic acidosis is associated with these 3 older NRTIs.
What is d4T, ddl, and ZDV?
300
DTG is metabolized by this.
What is UGT1A1?
300
These 2 ARVs interact with PPIs and are either contraindicated or require dose adjustment.
What is ATV and RPV?
400
Caution in patients with sulfa allergies.
What is DRV and FPV?
400
This NNRTI requires a two week dose escalation period because it induces its own metabolism and also to decrease risk for hepatotoxicity.
What is nevirapine?
400
This NRTI can be given as a continuous infusion to decrease MTCT.
What is zidovudine?
400
Stribild can only be started in patients with this CrCl, and it should be discontinued in patients already taking it if their CrCl drops below this value.
What is > 70 ml/min and < 50 ml/min?
400
This class of ARTs requires intracellular phosphorylation before it can work at its site of action.
What is NRTIs?
500
These two PIs have been associated with QT prolongation.
What is LPV and SQV?
500
Some clinicians recommend increasing the dose of this NNRTI when given with rifampin.
What is EFV? (600 to 800 mg based on PK models. Would use 600mg, could check trough, goal 1000 ng/ml)
500
Associated with high level resistance to 3TC and FTC, but may increase susceptibility to TDF and ZDV.
What is the M184V mutation?
500
These 2 populations require twice daily dosing of DTG.
What is integrase inhibitor experienced patients (INI resistance) and co-administration with UGT1A/CYP3A inducers?
500
Name the components and brand names of the four available one pill once daily regimens.
What is Atripla (TDF/FTC/EFV), Complera (TDF/FTC/RPV), Stribild (EVG/COBI/TDF/FTC), and Triumeq (ABC/3TC/DTG)?