NRTIs
NNRTIs
Entry, Fusion, & Integration Potpourri
PIs
The Name Game
100
The generic names for these antiretrovirals, notorious for causing pancreatitis and peripheral neuropathy.
What are didanosine and Stavudine?
100
The abbreviation for the NNRTI known for causing vivid dreams and other Central Nervous System effects.
What is EFV?
100
Abbreviation of the antiretroviral that is dosed based on the presence of other agents that inhibit or induce CYP3A4.
What is MVC?
100
The dosage form of this "booster" can be stored at room temperature.
What is a tablet?
100
Brand name for this one: AZT/3TC
What is Combivir?
200
This branded product contains 2 NRTIs with activity against Hepatitis B Virus.
What is Truvada?
200
The brand name for this NNRTI, known for causing high rates of hepatotoxicity in patients with high baseline CD4 counts.
What is Viramune?
200
This brand named injectable agent is known for it's potential for increased risk of pneumonia.
What is Fuzeon?
200
This branded drug product is known for nephrolithiasis and QTc prolongation. Pass on high dose proton pump inhibitors, please.
What is Reyataz?
200
ABC/3TC/AZT
What is Trizivir?
300
The abbreviation for this agent which is phosphorylated twice before being incorporated into a growing DNA strand.
What is TDF?
300
The brand name for this second generation NNRTI, known for higher rates of virologic failure in patients with baseline viral loads >100,000 copies/ml.
What is Edurant?
300
This branded product is the only integrase inhibitor that doesn't interact with strong CYP3A4 inducers.
What is Isentress?
300
The dosage form of the only product containing a protease inhibitor with it's own booster gets stored in the fridge.
What is solution?
300
Edurant with Truvada
What is Complera?
400
The generic name for this NRTI known for causing myopathy and gastrointestinal upset.
What is Zidovudine?
400
This generic named product is a NNRTI given twice daily and can also be dispersed in water if patients are unable to swallow it.
What is Etravirine?
400
The abbreviation of the integrase inhibitor boosted by cobicistat in the "quad" pill.
What is EVG?
400
The abbreviation for this one- it's got a sulfa moiety so be cautious. It can be given once or twice daily, but don't skimp on the boosting. Oh, and no worries about the fridge.
What is DRV?
400
Abbreviations for the components of Stribild
What is FTC/TDF/EVG/COBI?
500
The NRTI most structurally similar to FTC is combined with a drug that's a "no-no" when HLA-B*5701 is (+) in this pill.
What is Epzicom?
500
The only FDA-approved brand named single tablet regimens that each contain one NNRTI with 2 NRTIs.
What are Complera and Atripla?
500
This integrase inhibitor may be the new kid on the block, but it may be active despite Raltegravir resistance. Just don't take it with Tums.
What is Tivicay (or Dolutegravir)?
500
Hepatitis, skin rash and cerebral hemorrhage make this brand named product less desirable. Keep it cool.
What is Aptivus?
500
Truvada, Complera, Atripla, Stribild and Viread all contain this generic named drug.
What is Tenofovir?
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