Topic 1: Cell Communication
Topic 2-3: Signal Transduction
Topic 4-5: Signal Transduction Pathways and Feedback
Topic 6: Cell Cycle
Topic 7: Regulation of Cell Cycle
100
Animal cells communicate through ____ junctions, not plasmodesmata, like plants.

What is gap?

100
What are the three stages of cell signaling?

What is reception, transduction and response?

100

What results from the inability to regulate cell growth?

What is cancer?

100

How many sister chromatids are in a human cell?

What is 46?

100

What will happen to a cell if it does not pass the G1 checkpoint?

What is "it will enter the G0 phase where the cell does not divide and stays dormant?"

200

Animals and plants use this type of signaling for long distances.

What is endocrine signaling?

200

True or false: the final molecule in a signal transduction pathway can act as a transcription factor, so it can turn genes on or off.

What is "true?"

200

True or false. Not all normal, healthy somatic cells have the ability to maintain homeostasis.

What is "false?"

200

What is chromatin?

Strings of nucleosomes (DNA) form chromatin.

200

Describe what will happen to a cell if it does not pass the G2 checkpoint.

The cell will undergo apoptosis.

300

True or False? Paracrine signaling releases local regulators via exocytosis to an adjacent cell. 

What is true?

300

Where are estrogen receptors found in the cell?

What is "In the cytoplasm?"

300

Temperature regulation is a type of ______________ feedback.

What is "negative?"

300

What are the four main stages of mitosis?

What is "Prophase, Metaphase, Anaphase and Telophase?"

300
List the three types of external cell regulators.

What are "growth factors, contact inhibition, and anchorage dependence?"

400

Insulin signaling is an example of long distance signaling. In what specialized cells do insulin originate?

What are the beta cells of the pancreas?

400

True or false. Protein kinases phosphorylate (relay) the signal, while phosphatase dephosphorylates (stops) the signal.

What is "true?"

400

If a receptor protein is mutated, why can't it receive a ligand?

What is "its receptor may be damaged or changed?"

400

If a gamete has 20 chromosomes, how many chromosomes would the somatic cells have?

What is 40?

400

How are cancer cells able to leave the original tumor site and metastasize?

They no longer have anchorage dependence and move through the circulatory or lymphatic system.

500
True or false? Synaptic signaling occurs in animal and plant cells.

What is false? (synaptic signaling only occurs in animal nervous system cells)

500

What do second messengers do?

What is "they relay and amplify the message and the response?"

500

How can chemicals activate or inhibit a pathway?

Protein kinases relay the ligand through phosphorylation, or they inhibit the pathway using protein phosphatases.
500

Does mitosis occur in somatic or gametic cells?

What is "somatic?"

500

What are two ways a cancer cell differs from a normal cell?

They do not follow checkpoints, divide infinitely and evade apoptosis.

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