Cell Communication
Introduction to Cell Signaling
Signal Transduction Pathways
Feedback Loops
Cell Cycle and Regulation
100

The three stages of cell communication in order are Reception, Transduction, and... 

What is Response?
100

Put them in order:

response, ligand, receptor 

1. Ligand 2. receptor 3. response 

100

This is the primary function of a phosphorylation cascade, allowing a single ligand to trigger a massive cellular output 

What is signal ampification?

100
The component of a feedback system that processes information and determines the response 

What is a control center? 

100

The phase of the cell cycle during which DNA is replicated 

What is the S phase? 

200

In the first stage of cell communication, the specific chemical messenger that binds to a target receptor to initiate a cellular response is called a... 

What is a ligand? 

200

This protein enzyme catalyzes the conversion of ATP into cyclic AMP(cAMP) in response to an extracellular signal

What is adenylyl cyclase?

200

Draw what phosphorylation does to a protein

protein with an added phosphate group, turning ATP to ADP

200

Draw a simple negative feedback loop 

stimulus -> response -> returns system to normal conditions 

200
Draw the cell cycle as a circle and label the major phases

Include G1, S, G2, M 

300

This specific type of local signaling occurs when a cell secretes a local regulator(like a growth factor) to affect an adjacent or nearby target cell

What is paracrine signaling? 

300

Because they are polar and cannot cross the lipid bilayer, these receptors are located on the plasma membrane. 

What are membrane-bound receptors?

or

What are cell surface receptors?

300

Proteins that add phosphate groups to other proteins during signal transduction

What are protein kinases?

300

The maintenance of relatively stable internal conditions despite external changes 

What is homeostasis? 

300

Cell death that is genetically programmed and regulated

What is apoptosis?

400

Neurons in the nervous system use this form of local chemical signaling by releasing molecules into the synapse. 

What is Synaptic Signaling? 
400

The addition of a phosphate group to a protein, a key protein modification in signal transduction pathways

What is Phosphorylation?

400

A substance that blocks a receptor and prevents a signal from being received 

What is an inhibitor (or antagonist)?

400

definition of positive feedback loops AND a list of examples 

Definition: a mechanism that increases the output of a process in response to a stimulus

Examples: childbirth contractions, blood clotting, fruit ripening, breastfeeding

400

Draw and label the stages of mitosis in order.

Prophase -> Metaphase -> Anaphase -> Telophase 

500

This gaseous plant hormone is a famous example of long-distance chemical communication that travels through the air to induce fruit ripening. 

What is Ethylene?

500

small, nonprotein, water-soluble molecules or ions that quickly spread throughout the cell to relay a signal received at receptors on the cell surface

What are secondary messengers?

500

The uncontrolled division of cells resulting from disruptions in cell signaling

What is cancer?

500

The hormone released during labor that intensifies uterine contractions.

What is oxytocin?

500
The process that divides the cytoplasm into two daughter cells 

What is cytokinesis?

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