History of Anesthesia
The number of medical properties were accounted form in the first pharm book
What is 360; antispetic, antiinflammatory, menstral cramps, psych problems
Discorides Materia medica, 5 volumes
The RAS is located here.
anesthesia and sleep inhibit these and reversibly inhibit the CNS
Deep Sedation has what responsiveness level?
Repeated or painful stimulation.
vs GA is not responsive to pain to stimulation!
Famotidine E1/2
2.5-4 hours
longest e1/2 and most potent
EEG stands for
electroencephalogram
Levy discovered this about a certain anesthetic
what is light chloroform + adrenaline = fatal
GABA stands for
Gamma aminobutyric acid
Stage 3 3rd plane
Beginning to completion of intercostal muscle paralysis, pupil dilation; desired plant prior to muscle relaxants
Lansoprazole (prevacid) is what type of drug?
PPI
Dose range for a flumazenil gtt
.1-.4mh/hr
Year was the 1st successful public demonstration of ether
what is 1846
Letheon at mas gen.
Alpha 2 is located here
Hippocampus, amygdala
Metabolism in the plasma undergoes this process
Hoffman elimination and ester hydrolysis (some nmb)
Omeprazole (prilosec) dose
40mg in 100 cc NS over 30 min or po >3 hrs prior to OR
What is the name of mary's dog
COBIE!!
The first inhalation anesthetic was made from these items.
what is sulfuric Acid and ethyl alcohol
Diethyl ether made by valerius Cordus
Valium's active metabolites and their timespan
Desmethyldiazepam (48-96 hours) and oxazepam
nearly as potent as parent
return to drowsiness 6-8 hours
You gave 4 ml of Roc that have a concentration of 250 mcg/5ml. The E1/2 is 240 min. what is the concentration of fent in the plasma 12 hours after injection.
12.5 mcg
200 at injection ->100->50->25 -> 12.5
Tagamet adverse effects
bradycardia, hypotension, inc plasma levels of prolactin, impotence (inhibits dihydrotestosterone binding to androgen R)
What does BIS stand for
Bispectral Analysis
The elements used for soporifics
What is;
1/2 ounce of opium
Just of mandrake leaves
Juice of hemlock
3oz of hyposyamus
water
Reversal = vinegar
Diazepam induction dose
0.5-1 mg/kg IV
Name of process to covalently link with a highly polar molecule to become more water soluble?
conjugation
phase 2 -> conjucation -> pee off
Long Term use of antacids cause these things
Acid breakdwon of food inhibited and acid rebound can occur
mag - osmotic diarrhea and nm impairment
calcium- hypercalcemia (kidney stones)
sodium- increased na load (htn/ chf pts)
Verseds active metabolite
1 hydroxymidazolam
1/2 as active as parent