General Properties
Genome of arbovirus
RNA+
Name the Alpha virus common in India
Chikungunya
Clinical features of Yellow fever
Jaundice, albuminuria and hemorrhagic manifestations develop and the patient may die of hepatic or renal failure.
Name the personal protection used as preventive measure
Bed net, Repellants, Protective clothing
Genome of Rhabdoviruses?
RNA-
Why its known as Arbo virus?
Arthropod and rodent Borne Virus
Chikungunya is transmitted by which vector?
Aedes aegypti mosquito
classical dengue is called
Break bone Fever
name the vaccines available for yellow fever
17 D vaccine
Dakar- Neurotropic vaccine
Morfology of RABIES VIRUS
The rabies virus is bullet shaped, 180 x 75 nm in size, with one end rounded or conical and the other planar or concave.
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Name 3 symptoms of Chikungunya
Crippling Joint Pain,
Fever, rash
Conjunctivitis
lymphadenopathy ( Any 3 of these)
Name the viral proteins associated with dengue virus
E protein
M protein
C protein
How to control Dengue ?
Mosquito eradication
Removal of breeding place
personal protection from mosquito bite
Intracytoplasmic inclusion bodies founded in patients with Rabies?
Negri bodies
Call main clinical entities that Arboviruses produce?
Arboviruses produce three main clinical entities:
Fevers with or without rashes
Hemorrhagic fevers
Encephalitis
Name 4 Alphaviruses causing encephalitis
EEE, WEE, VEE, Semliki forest Encephalitis
Geographical distribution of Japanese encephalitis in the world.
This virus occurs from East Asia to South Asia, from Korea and Japan in the north to India and Malaysia in the south.
vector control measure
Pesticides
elimination of breeding place
hygeine
Pathogenesis of Rabies
EXPOSURE Bite from rabid animal infection with rabies virus
INCUBATION PERIOD Multiplication of rabies virus within new host (20-90 days)
FIRST SYMPTOMS Spead of virus through nerve endings to central nervous system virus reaches the brain
PRODROMAL STAGE Early symptoms include pain or paresthesia at site of inoculation and (2-10 days) other non-specific flu-like symptoms (e.g. malaise, fever, headache
FIRST NEUROLOGIC SIGNS Symptoms include cerebral dysfunction, anxiety, confusion, agitation
ACUTE Progression to delirium, abnormal
NEUROLOGIC PHASE behaviour, hallucinations, insomnia, (2-10 days) hydrophobia, aerophobia and photophobia
ONSET OF COMA Coma (0-14 days)
DEATH
Name the Vectors and reservoirs of arboviruses
Vectors - Mosquito, Ticks, sandfly
Reservoirs - Birds, Pigs, Monkey & Rodents
Genotypes of Chikungunya virus.
There are three major ccccgenotypes:
• West African
• East/Central/South African (ECSA)
• Asian genotypes
Tick-borne encephalitis viruses are transmitted by the bite of ...
Ixodid ticks
Is there a vaccine for Japanese encephalitis?
Yes or no?
Yes
Post-exposure prophylaxis of Rabies/
Doses and intervals between them
Post-exposure prophylaxis requires five or six doses, on days 0, 3, 7, 14, 30 and optionally 90