What is the function(s) of mucus in the body?
Lubrication
Waterproofing
Protection from inflammation
What anti-inflammatory medications are indicated when treating asthmatics and patients with chronic obstructive pulmonary disease (COPD)?
Corticosteroids
Neutrophils are the primary inflammatory cells associated with which of the following diseases?
COPD
Extrinsic asthma is dependent on what factors?
Allery and Atopy
Nonsteroidal antiasthma drugs are controllers that require:
Anti-inflammatory drug therapy
There are more than ___________ goblet cells per square millimeter of normal airway mucosa is
6,000
Acetylcysteine is incompatible in solution with
Tertacycline, Amphotericin B, Sodium, ampicillin
Hypersecretion or poor clearance of secretions are signs of
CF, Primiary ciliary dyskinesia, Pneumonia
The _______ phase of an asthmatic reaction occurs during the 15 min to 1 hour time frame?
Early
What type of lymphocytes plays a central role in attracting mast cells and eosinophils
T lymphocyte
Expectorants agents increase volume or hydration of airway secretions by stimulating:
Bronchial gland
List the examples of steroids or steroid combinations available for inhalation?
1. Pulmicort
2. Flovent
3. Qvar
4. Advair
The production of glucocorticoids in the body follow what kind of rhythm?
Circadian
Use of glucocorticoid steroids for long periods can lead to:
Adrenal suppression
Which type of helper T cell, Th1 or Th2, is involved primarily in the atopic allergic response?
Th2
Medications that improve the mobilization and clearance of secretions are:
Mucokinetics
An expectorant that has been approved by the FDA in the for a bilayer extended-release tablet is:
Guaifenesin
You have a patient with cystic fibrosis (CF) who needs an aerosol medication to reduce the viscosity and adhesivity of infected respiratory secretions. What agent would you recommend?
Mucoactive agent
The steroids that help with regulating body water and sodium reabsorption:
Mineralocorticoids
____________ are considered the major effector cells of the inflammatory response, regardless of whether asthma is allergic or nonallergic:
Mast cells and Eosinophils
Name the response that causes an increase in mucus production and mucus transport that effects the involvement of mucociliary clearance
The cholinergic response in terms of mucociliary clearance involves an increase in ciliary beat, an increase in mucus production, and an increase in mucus transport.
Cromolyn sodium is effective in preventing bronchospasm by:
Blocking release of the chemical mediators
Mast cell degranulation inhibition
Montelukast
What is the effect of orally administered corticosteroids on growth, bone density, and adrenal function?
Growth is decreased in children; bone density is decreased, causing osteoporosis; normal adrenal steroid secretion is suppressed, and in general the hypothalamic–pituitary–adrenal (HPA) axis activity is suppressed.
The process of inflammation is caused by the following four major categories of activity
1. Increased vascular permeability
2. Leukocytic infiltration
3. Phagocytosis
4. Mediator cascade