Arzerra was used in combination with this agent in the Phase III trial in untreated CLL
What is chlorambucil
100
All approved doses of Arzerra should be prepared in this volume of normal saline
What is 1000 mL?
100
The most common adverse events (≥10%) in the Ph3 clinical trial for untreated CLL
What are infusion reactions and neutropenia?
100
Ibrutinib (Imbruvica™) is a member of this novel class of agents
What is Bruton’s Tyrosine Kinase (BTK) inhibitors?
100
Approved in Canada, the generic name for Incruse Ellipta
What is umeclidinium?
200
The number of the MI response that focuses on Study 911
What is RSP38689?
200
A prepared solution should be discarded after this length of time
What is 24 hours?
200
These are included in the boxed warning for Arzerra
What are Hepatitis B Reactivation and Progressive Multifocal Leukoencephalopathy (PML)?
200
The generic name for Gazyva™, a CD20 antibody recently approved for previously untreated CLL
What is obinutuzumab?
200
The GLP-1 biologic product recently approved for once-weekly treatment of Type 2 diabetes
What is Tanzeum (albiglutide)?
300
This MI response includes data on 4 trials in previously untreated CLL
What is RSP38682?
300
Once a requirement for administration, this device is no longer needed for Arzerra administration, although packaging may contain this for several months.
What is the in-line filter set?
300
Infusion reactions may occur despite premedication with these 3 agents
What are acetaminophen, corticosteroid, and antihistamine?
300
This oral inhibitor of PI3K delta is also known as CAL-101 and GS1101
What is idelalisib?
300
This product is umeclidinium /vilanterol, indicated for COPD
What is What is Anoro Ellipta?
400
Another name for Study 911
What is COMPLEMENT 1?
400
For 1L CLL, after the 300 mg initial dose, this dose of Arzerra is administered for a minimum of 3 cycles until best response or a maximum of 12 cycles
What is 1000 mg?
400
For this W&P, consider prophylaxis with anti-hyperuricemics and hydration beginning 12 to 24 hours prior to infusion of Arzerra
What is tumor lysis syndrome (TLS)?
400
This NCCN recommended comb. regimen for 1st-line CLL includes a recently approved CD20 MaB
What is obinutuzumab (Gazyva™) + chlorambucil?
400
This product is fluticasone furoate /vilanterol, indicated for C-O-P-D
What is Breo Ellipta?
500
The primary endpoint in Study 911, this was significantly greater for Arzerra plus chlorambucil, vs. chlorambucil monotherapy
What is median PFS?
500
In the absence of infusion-related adverse events, the infusion rate of Arzerra may be increased at this interval
What is 30 minutes?
500
This cytopenia can occur during treatment, as well as with late onset and prolonged
What is neutropenia?
500
This monotherapy for R/R CLL was approved February 2014 and is recommended in the NCCN Guidelines
What is ibrutinib (Imbruvica™)?
500
This once-daily tablet, known as dolutegravir, is indicated for the treatment of HIV infection