Rheumatoid arthritis
What type of autoimmune disease is rheumatoid arthritis?
Autoimmune inflammatory disease
What genetic marker is associated with ankylosing spondylitis
HLA-B27
What is the characteristic crystal shape seen in gout?
Needle
Which of the following joints are commonly affected early in the rheumatoid arthritis ?
MCP and pip joints
What joint is characteristically affected in axial spondyloarthritis?
Sacroiliac
What type of bone is primarily affected in osteoporosis?
Trabecular
35 year old women has morning stiffness lasting 2 hours,symmetrical swelling of the mcp and pip joints,and symptoms of 3 months.
Which findings would most strongly support a diagnosis of rheumatoid arthritis?
Anti ccp antibodies
A patient develops arthritis after a gastrointestinal infection. What type of spondyloarthritis is suspected?
Reactive
What vertebral deformity can result from osteoporotic compression fractures?
Kyphosis
A 42-year-old woman presents with pain and swelling of both wrists, MCP and PIP joints for 8 months. She has prolonged morning stiffness. Examination shows symmetrical synovitis. Laboratory tests show elevated ESR and CRP, positive rheumatoid factor, and positive anti-CCP antibodies. X-ray shows marginal erosions.
Which mechanism best explains the joint destruction in this patient?
Chronic synovial inflammation with pannus formation and activation of osteoclasts
What eye condition is commonly associated with ankylosing spondylitis?
Uveitis
What type of crystals are seen in gouty synovial fluid?
Monososdium-urate
A 50-year-old woman with long-standing rheumatoid arthritis develops progressive neck pain and neurological symptoms. Imaging shows erosion of the odontoid process with increased movement between C1 and C2.
Which complication is most likely, and what is the underlying pathological process?
Atlantoaxial subluxation due to inflammation and destruction of the transverse ligament/atlantoaxial structures
What eye condition is commonly associated with ankylosing spondylitis?
Psoriatic
What score is used to diagnose osteoporosis in post menopausal women?
T score