Sleep physiology
Major inhibitory neurotransmitter in the brain
What is GABA
The primary role of orexin
Stabilize wakefulness and regulate the sleep-wake cycle
Statins inhbit this enzyme
What is HMG-CoA Reductase
Increases BMI in mice and humans
What is CLOCK gene mutations
Stage of sleep that is characterized by delta waves
What is NREM stage 3
Symptoms that result from lack of orexin in the brain
Daytime sleepiness, cataplexy, sleep paralysis, and hallucinations
This system lowers blood pressure at night
What is the Renin-Aldosterone Angiotensin System
Increases the risk of hormone-related cancers due to increased estradiol synthesis
Melatonin secretion
Controls the circadian rhythm
What is the suprachiasmatic nucleus
Three examples of DORAs
These two transcription factors aid in the circadian rhythm
What is Bmal1 and CLOCK
Cancer chronotherapy is dependent on this
What is DNA repair