Unit 1
The ideal neuron for long range signaling has..
(high/low) time constant
(high/low) length constant
low time constant
high length constant
This type of plasticity is common at synapses with high release probability.
What is short term depression?
The photoreceptors that detect color.
What are: Cones
This motor pathway, primarily involving D2 medium spiny neurons (MSNs) that is impaired in Huntington's disease.
What is the indirect pathway?
A lesion here may cause dysmetria.
What is the spinocerebellum?
What concept explains why action potentials only travel in one direction down an axon?
Inactivation of voltage-gated sodium channels
This type of recording method has amplitudes of less than 10 pA.
What is single channel patch clamp?
The types of neurons that degenerate in Huntington's Disease
What are: Medium spiny neurons in the Striatum (Basal Ganglia)
A lesion here in the spinal cord would inhibit touch sensation.
What is the dorsal column?
This projection induces plasticity at the granule cell/purkinje neuron synapse.
What is a climbing fiber?
If extracelluar K+ was decreased, what would happen to the resting membrane potential?
hyperpolarized
This class of channels are sensitive to both heat and chemical signal.
What are TRP channels?
The apex of the basilar membrane encodes this.
What are: Low-frequency sounds
The cell bodies of sensory neurons of the PNS are here.
What is the DRG?
This type of cell can excite or inhibit purkinje neurons.
What is a granule cell?
If a neuron's membrane potential is at -70 mV and the equilibrium potential for Na is +60 mV, which direction is the sodium current?
Inward (into the cell)
Upregulation of this protein decreases activation of acetylcholine receptors at the NMJ through breakdown of acetylcholine in the synaptic cleft.
What is acetylcholinesterase?
This is where the touch pathway crosses over to the contralateral side:
What is: The medial lemniscus (Medulla, brainstem)
This classic experiment demonstrated how the brain combines visual inputs of simple patterns to reveal information about motion processing in the brain. Explain the experiment.
What is the stripes and plaids experiment?
V1...
MT...
This type of plasticity in the cerebellum is induced by a low influx of calcium.
What is cerebellar LTP?
Describe the basics of a current clamp experiment
current injected is held constant, voltage is measured
The structural domain of voltage gated sodium channels responsible for inactivation.
What is the DIII-IV link?
What are: C-fibers
Why are slow motor fibers (small motor units) recruited first?
What is high input resistance?
The major output center of the cerebellum.
What is the deep cerebellar nucleus?