Schizophrenia Presentation
Medication Selection
Side Effect Management
Long-Acting Injectables (LAIs)
Treatment-Resistant Cases
100

A 22-year-old male presents with auditory hallucinations, paranoia, and disorganized speech for the past 8 months. He has been socially withdrawn and unable to maintain employment.

What is Schizophrenia?

100

What is the first-line medication for schizophrenia in a newly diagnosed patient without metabolic concerns?

What is Aripiprazole (Abilify)?

100

A patient on Risperidone develops galactorrhea and amenorrhea. What is the next best step in management?

What is switch to Aripiprazole?

100

What LAI requires a 3-week oral overlap when initiating treatment?

What is Risperdal Consta?

100

What is the next step for a patient who has failed two trials of antipsychotics with persistent positive symptoms?

What is Clozapine initiation?

200

A 30-year-old female reports hearing voices criticizing her actions for the past 2 weeks after losing her job. She denies drug use or a prior psychiatric history.

What is Brief Psychotic Disorder?

200

Which antipsychotic requires routine ANC monitoring due to the risk of agranulocytosis?

What is Clozapine?

200

A patient presents with acute dystonia after receiving an injection of Haloperidol. What medication should be administered?

What is Benztropine or Diphenhydramine?

200

Which LAI is administered monthly without requiring oral supplementation?

What is Invega Sustenna (Paliperidone)?

200

What monitoring is required for Clozapine treatment?

What is regular ANC monitoring?

300

A 45-year-old male with a history of bipolar disorder presents with grandiose delusions and auditory hallucinations during a manic episode.

What is Schizoaffective Disorder?

300

This antipsychotic has the lowest risk of weight gain but must be taken with food for adequate absorption.

What is Ziprasidone (Geodon)?

300

A patient taking Olanzapine presents with significant weight gain and increased fasting glucose. What is the management approach?

What is switch to a lower metabolic risk SGA such as Aripiprazole or Ziprasidone?

300

A patient with poor adherence to oral antipsychotics is being considered for an LAI. Which medication is a good first option?

What is Aripiprazole Maintena?

300

A patient with schizophrenia and metabolic syndrome is experiencing significant weight gain. What medication is a better alternative?

What is Ziprasidone or Aripiprazole?

400

A patient presents with delusions that his neighbor is poisoning his food. He has no hallucinations or disorganized speech and functions well socially.

What is Delusional Disorder?

400

Which first-generation antipsychotic is commonly used for acute agitation but has a high risk of extrapyramidal symptoms?

What is Haloperidol (Haldol)?

400

A patient on antipsychotics develops tremors, rigidity, and bradykinesia. What side effect is this?

What is Drug-Induced Parkinsonism?

400

Which LAI requires monitoring for post-injection sedation and delirium?

What is Zyprexa Relprevv (Olanzapine)?

400

A patient on Clozapine presents with tachycardia, fever, and flu-like symptoms. What condition should be suspected?

What is Clozapine-induced myocarditis?

500

A 19-year-old male presents with symptoms of schizophrenia that have persisted for 4 months. What is the likely diagnosis?

What is Schizophreniform Disorder?

500

Which antipsychotic is considered the most effective for treatment-resistant schizophrenia?

What is Clozapine?

500

A patient on an FGA presents with muscle rigidity, autonomic instability, and hyperthermia. What is the likely diagnosis?

What is Neuroleptic Malignant Syndrome (NMS)?

500

Which LAI is an option for patients experiencing hyperprolactinemia on Risperdal?

What is Aripiprazole LAI?

500

Which antipsychotic has the highest affinity for D3 receptors and is beneficial for negative symptoms?

What is Cariprazine (Vraylar)?

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