Gram - IV
Why are mature hosts more susceptible to Brucellosis?
Sexual maturity of reproductive
"allantoic growth factor"
What post-infectious syndrome is associated with Campylobacter jejuni and what does it cause?
Guillan-Barre syndrome
demyelination of peripheral nerves
Why is it important to test both blood and urine in cases of suspected Leptospirosis?
Disease is biphasic in early phase it is detectable in blood, in late phase it is detectable in urine
What antimicrobial class is used to treat almost all obligate intracellular bacteria?
Tetracyclines
Genus Trichophyton and genus Microsporum share what common name?
Ringworm
What immune cells do Brucella spp. facultatively invade?
macrophages
What site acts as a reservoir of Campylobacter fetus in bulls?
Preputial crypts (microaerophilic environment)
What disease state does Leptospirosis cause in horses?
Equine Recurrent Uveitis
What genus is referred to as an energy parasite due to its inability to produce its own ATP?
Chlamydia
What species is the major asymptomatic carrier of Microsporum canis?
Cats
What disease states does Brucella abortus produce in horses?
poll evil-septic arthritis of atlanto-occipital joint
fistulous withers
Helicobacter hepaticus and Helicobacter bilis infect what species?
Mice
What clinical signs are associated with Borrelia burgdorferi in dogs?
fever, acute arthritis, lameness
What highly zoonotic bacteria persists in environment as an "endospore-like" form?
Coxiella burnetii-Q
Microsporum gallinae causes ringworm in what species?
Avian
What Brucella spp. is not associated with zoonosis?
Brucella ovis
What lesion is associated with Lawsonia intracellularis in pigs and horses?
cerebriform or gyrate pattern (brain-lookin) in ileum and colon
What species causes swine dysentery in growing pigs?
Brachyspira hyodysenteriae
What cells do members of Anaplasmataceae infect?
Hematopoietic cells
What is the difference between ectothrix and endothrix dermatophytes?
ectothrix- outside hair follicle
endothrix- inside hair follicle
Describe the mallein test and what species it is meant to detect.
protein fraction introduced to eye
swelling 48 hours post is indicative of infection
Burkholderia mallei (Glander's disease)
What is the primary virulence factor of Helicobacter and what is its function?
extracellular urease
acid neutralization
What species causes Rabbit syphillis (Vent disease)?
Treponema paraluiscuniculi
True or False: Ehrilichia canis infects macrophages
FALSE
circulating monocytes
Describe the action of Griseofulvin
oral administration - systemic circulation to keratinized epithelium - inhibits fungal DNA synthesis