what is the indication for Baxfendy?
indicated for the treatment of hypertension, to lower blood pressure in adults who are not adequately controlled on other agents.
What is the primary end point and results of BAX HTN
change in seated SBP with baxfendy 2mg from baseline to week 12
-15.7 mm Hg
What eGFRs were included in the trial
eGFR >45mL/min/1.73m
what is the maximum cash value of the co-pay card
$100
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Rosa
What are the contraindications?
there are no contraindications
What is the efficacy of Bax 1mg?
14.5 mm Hg
there were no reports of ____ in BaxHTN and Bax24
adrenal insufficiency
gynecomastia
Who can contact the baxfendy access navigator
office staff
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Jacob
What other class of drugs should baxfendy not be taken with?
MRAs and CYP3A
Bax 24 primary endpoint and results
change in 24-hour ambulatroy SBP with bax 2mg from baseline to week 12
-16.6 mm Hg
what are the doses of Baxfendy
2mg starting and maintenance
1mg for those with increased risk of hyperkalemia or hyponatremia
What is the role of ASPN pharmacy
conduct benefit verification
supports PA's
applied discounts
offers home delivery or pharmacy pick up
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who is Melia
When should you test serum potassium levels
before and periodically there after
what were the background antihypertensive medications in the overall population and their %'s in Bax HTN
diuretic: 100%
ACEi/ARB: 90%
CCB: 70%
Beta Blocker: 34%
What were the rates of Hyperkalemia, hypotension and hyponatremia in Bax 2mg v 1mg
2mg: 10.2%, 3.6%, 3.2%
1mg: 6.6%, 2.1%, 2.1%
What is the process for a commercially insured patient that is insured/covered vs insured/not covered
insured/covered: runs co-pay card normally with coverage code 8 gets cost to $15
insured/not covered: when cost comes back >$50 run co-pay with over coverage code 3 to get cost to $15
Sydney
Mean baseline of serum potassium levels of patients during the study
4.2 mmol/l
what % of patients achieved an ambulatory SBP <130 for 24hours?
71%
what are the discontinuation rates of both doses due to hyperkalemia
2mg: 1.8%
1mg: 0.6%
How can a medicare patient get Baxfendy
prescribe the patient Baxfendy and be prepared to do a PA or ME. an appeal might be needed as well if the prior auth or medical exception gets denied .
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Chelsea