HIV
The 1981 MMWR report describing Pneumocystis pneumonia in 5 men in Los Angeles marked the first recognition of this epidemic.
What is HIV/AIDS?
This intestinal ciliate protozoan is the largest infecting humans and can cause dysentery-like illness.
What is Balantidium coli? Associated with areas with pigs
This viral hemorrhagic fever was first identified in a 1967 outbreak among lab workers exposed to infected African green monkeys.
What is Marburg virus?
This triad of conjunctivitis, urethritis, and arthritis is associated with certain post-infectious states, especially after Chlamydia infection.
What is Reiter’s syndrome (reactive arthritis)?
This scientist discovered penicillin in 1928.
Who is Alexander Fleming?
This opportunistic infection is the leading cause of blindness in people with untreated AIDS.
What is CMV retinitis?
This rare parasite, causing severe CNS disease, can be acquired through ingestion of raw freshwater fish and is known for its “coiled tail” appearance.
What is Gnathostoma spp.?
This bacterial infection, transmitted by fleas, caused the “Black Death” in medieval Europe.
What is Yersinia pestis (plague)?
This rare complication of EBV infection involves hemophagocytic lymphohistiocytosis (HLH) and multiorgan failure.
What is EBV-associated HLH?
This physician linked puerperal fever to hand hygiene in 1847.
Who is Ignaz Semmelweis?
This coreceptor, along with CD4, is required for HIV entry into T cells.
What is CCR5 (or CXCR4)?
This protozoan, associated with severe diarrhea in AIDS patients, can cause “auto-infection” via thin-walled oocysts.
What is Cryptosporidium parvum?
The “Kuru” disease outbreak in Papua New Guinea was linked to this cultural practice.
What is ritualistic cannibalism?
This triad of chorioretinitis, hydrocephalus, and intracranial calcifications is associated with congenital infection by this parasite.
What is Toxoplasma gondii?
The acid-fast staining technique used for Mycobacterium species was developed by these two scientists.
Who are Ziehl and Neelsen?
This landmark 1996 trial demonstrated that combination antiretroviral therapy (cART) significantly reduced HIV-related morbidity and mortality.
What is the Delta or ACTG 320 trial?
This nematode, known for causing hyperinfection in immunosuppressed patients, penetrates human skin and autoinfects via the GI tract.
What is Strongyloides stercoralis?
This infectious disease was declared eradicated by the WHO in 1980.
What is smallpox?
This famous “Typhoid” carrier was responsible for multiple outbreaks in New York in the early 1900s.
Who is Mary Mallon (Typhoid Mary)?
This Nobel Prize winner developed the first effective treatment for syphilis, known as Salvarsan.
Who is Paul Ehrlich?
This monoclonal antibody targets the CD4 binding site of gp120 and is FDA-approved for multidrug-resistant HIV.
What is ibalizumab?
This flea-borne parasite burrows under the skin and is common in tropical climates.
Tunga penetrans (chigoe flea)
The first successful polio vaccine was developed by this American virologist.
Who is Jonas Salk?
Inactivated polio vaccine
Sabin: live attenuated
Originally described in young women, this histiolytic necrotizing lymphadenitis usually affects the cervical lymph nodes
Kikuchi disease or Kikuchi-Fujimoto disease
This scientist identified the mosquito as the vector of yellow fever, confirming Walter Reed’s theories
Who is Carlos Finlay?