Iboga Plant
The main active secondary metabolite in the Iboga plant
Ibogaine
Alkaloid
Dry and grind
Main property of ibogaine
These are tribes that traditionally used the Iboga plant (name one).
Babongo, Mitsogo, Fang, Bwiti, Mbiri
Lipophilic or hydrophilic
Lipophillic
Two solvents used to extract
Acetic acid and ammonia
Ibogaine treats this
Addiction, diabetes, flu, high blood pressure, and HIV/AIDS, mental health issues
Related plant that has an compound useful for semisynthesis.
Voacanga Africana
Noribogaine
Column Chromatography, HPLC, L-L partioning, Recrystallization
Main side effect and cause of this side effect
Cardiac, potassium channel interference
Apocynaceæ (Dogbane)
Ibogaine is chiral
True
Legality of ibogaine in the US
Illegal
Three secondary metabolites of the plant.
Ibogamine Ibogaine Ibogaline Noribogaine Voacangine Coronaridine Tabernanthine
Three parts of iboga alkaloids.
indole 7-membered tetrahydroazepine bicyclic isoquinuclidine
What is the percent yield of ibogaine from the plant
0.3%