Rebirth
This active item has a similar property to Goat Head but does not keep the deal door open.
What is Book of Belial?
This completion mark is the only one that can be earned by defeating either of two different bosses.
What is Heart?
A majority of Mom unlocks share this trait
What are Co-Op Baby items?
Reroll your destiny
What is The D6
Blood Bag
An item that was considered as a Special Item only in Rebirth
What is Soy Milk, Lil Brimestone, or Stopwatch
These 2 completion marks are obtained in the same chapter
What are Isaac and Satan?
A majority of Tainted unlocks from Delirium share this trait
What are unlocking an item associated with their ability?
...
What is Eden's Soul or Flush!
Counterfeit Penny
What is using a Shell/Hell beggar 100 times in total
The unlock process of The Lost
What is Isaac dies to Mulliboom in Chapter 1
Maggy dies to own bomb in Chapter 2
Judas dies to Mom in Chapter 3
Azazel dies to Satan in Chapter 4?
This completion mark requires accessing a special floor that only appears on a time limit
What is Hush?
The unlock items of Tainted Characters for Mega Satan
What are non-item unlocks?
It's time you learn how
What is How to Jump?
A Bandage
What is picking up Ball of Bandages 4 times?
The number of Quality 4 items from Rebirth (Quality value as of V.1.7.9b)
What is 16?
This completion mark is earned by defeating a final boss that locks in your ending as soon as you enter its path.
What is the Beast?
Judas, Azazel, Lilith, and Apollyon all possess this similarity.
What are locked icons being a statue?
Ascended
What is Dogma?
If only everyone was as generous as you...
What is Donate 999 to the Greed Donation Machine
These two items allow you to pay out a Blood Donation Machine for free without taking damage from the machine
What is Isaac's Heart and Holy Mantle?
This character can get all completion marks in one run
What is Tainted Cain?
Magic Skin, Pyro, Lead Pencil, and Plac C all share this trait.
What is possessing an item weight value of 0.1?
ZZaZZ ZZdZZiZZmZZhZZ ZZvZZ ZZoZZ ZZ ZZsZZlZZhZZsZZoZZaZZiZZ
What is TMTrainer?
Ace of Spades
What is kill The Lamb without taking bombs, hearts and coins the entire run