History
He developed the first vaccine using cowpox to protect against smallpox.
Who is Edward Jenner?
This immune system is the body’s first line of defense.
What is innate immunity?
An agent that causes disease.
What is a pathogen?
1. These cells produce antibodies.
2. These cells are responsible for cell-mediated immunity.
1. What are B cells?
2. What are T cells?
This condition results from loss of self-tolerance.
What is autoimmune disease?
This disease was declared eradicated in 1977 due to vaccination.
What is smallpox?
This immunity develops after exposure to a pathogen.
What is adaptive immunity?
A substance capable of eliciting an immune response.
What is an immunogen?
Helper T cells recognize antigens presented on this MHC class.
What is MHC Class II?
These researchers showed immunity could be transferred using serum.
Who are Von Behring and Kitasato?
This is the key feature that distinguishes adaptive immunity from innate immunity.
What is immunologic memory?
Any substance that binds specifically to an antibody or T-cell receptor.
What is an antigen?
This scientist demonstrated that white blood cells can engulf pathogens.
Who is Metchnikoff?
This feature allows adaptive immunity to distinguish between two antigens that differ by only one amino acid.
What is antigenic specificity?
The specific portion of an antigen recognized by immune receptors.
What is an epitope?
Anaphylaxis is associated with this antibody class.
What is IgE?
This scientist demonstrated that vaccination with a heat-attenuated pathogen could protect against a later infection with a virulent strain.
Who is Louis Pasteur?
This is the most accurate reason why the innate immune system cannot generate immunologic memory.
What is because innate immune receptors are germline-encoded and lack antigen-specific clonal expansion?