DNA replication
The genetic code
Basic DNA structure
DNA problems?
Transcription & translation
100

This enzyme is responsible for adding dNTPs to a growing nucleotide strand

What is DNA polymerase?

100

This is a nucleotide triplet that codes for an amino acid

What is a codon?

100

This is the pentose sugar in DNA.

What is deoxyribose?

100

This enzyme elongates the 3' overhang at the ends of chromosomes, providing a new site for an RNA primer to bind.

What is telomerase?

100

In eukaryotes, transcription factors get transcription machinery onto promoters. In bacteria, this piece of RNA polymerase is critical for it binding to a gene's promoter.

What is the sigma factor.

200

These are the building blocks of a new DNA strand; DNA polymerase adds them one at a time

What are dNTPs?

200

This is the first amino acid in most proteins; its codon is known as a start codon.

What is methionine?

200

In a DNA strand, this nucleotide pairs with thymine.

What is adenine?

200

Insertions and deletions are collectively called this type of mutation.

What are frameshifts?

200

In eukaryotes, this promoter is where the transcription machinery binds; it is usually immediately upstream of the RNA-coding region.

What is the core promoter?

300

DNA replication is continuous on the leading strand and discontinuous on this strand.

What is the lagging strand?

300

When we're deciding which three adjacent nucleotides should be read together as a codon, we're choosing this for a particular gene.

What is a reading frame?

300

Cytosine and thymine (and uracil, in RNA) are known as this type of nitrogenous base.

What are pyrimidines?

300

While silent mutations have no effect on encoded amino acids, and nonsense mutations introduce a stop codon, these mutations change the encoded amino acid to something else.

What are missense mutations?

300

In eukaryotes, in addition to faraway enhancers, this binds transcriptional regulators and affects the rate at which a gene is transcribed.

What is the regulatory promoter?

400
Before DNA polymerase can start making a new DNA strand, this must be laid down (and will later be replaced by DNA).

What is an RNA primer?

400

These codons have no corresponding tRNA and signal and end to translation

What are nonsense codons?

400

This description of a DNA strand reflects the fact that one strand's 5' end pairs with the other's 3' end, and vice versa.

What is anti-parallel?

400

If DNA polymerase doesn't do its job proofreading, repair enzymes can trim out the incorrect bases, and then DNA polymerase can add the right ones through this type of repair.

What is nucleotide excision repair?

400

This enzyme makes sure that tRNAs get hooked up with the right amino acid for translation.

What is aminoacyl tRNA synthetase?

500

This enzyme seals nicks in DNA that was replicated from the lagging strand.

What is DNA ligase?

500

An mRNA transcript is identical to the coding strand of DNA (except with U's instead of T's) and reverse complementary to this strand of DNA.

What is the template strand?

500

In contrast to the weaker hydrogen bonds that link bases from two strands of DNA, these stronger covalent bonds hold together adjacent nucleotides on a single strand.

What are phosphodiester bonds?

500

In bacterial mismatch repair, the original DNA strand has these added to it, distinguishing it from the new, incorrectly copied strand.

What are methyl groups?

500

In addition to tRNA and mRNA, this type of RNA is critical to translation. It is produced in a eukaryote's nucleolus. In addition to protein, it forms the protein-synthesizing organelles.

What is rRNA?

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