Chemistry
pH, Acids, & Bases
Amino Acids
Protein Folding
Proteins
100

The three components of an atom

What are protons, neutrons, and electrons?

100

What is an acid?

A substance that increases the hydrogen ion concentration of a solution

100

Amino acids make up____

proteins

100

What binds primary structure together?

Peptide bonds (covalent bonds)

100

What is an aquaporin?

An integral membrane protein that facilitates the movement of water across a membrane

200

How many valance electrons does nitrogen have?

5

200

pH = negative log of ____

the concentration of hydrogen ions [H+]

200

What reaction makes the bonds between the amino acid chain?

Dehydration synthesis

200

True or False: Quaternary structure exists in all proteins.

False

200

What causes protein denaturation?

Heat, shifts in pH, and alcohols/salts of heavy metals

300

Which compound is least likely to dissolve in water?

NaCl, CH3, NH3, C2H6O, or C6H6

C6H6

300

2 water molecules can dissociate into _____ and _____

A hydronium ion (H3O+); hydroxide ion (OH-)

300

What four questions do you ask when evaluating amino acids?

Is it polar?
Is it nonpolar?
Is it positively charged/a base?
Is it negatively charged/an acid?

300

What are the two types of secondary structure?

Alpha helices & Beta sheets


300

What is the purpose of the iron of a heme group?

To interact with O2 with just the right strength in order to carry it.

400

Order the atoms from highest electronegativity to lowest: O, Br, Si, F

F > O > Br > Si

400

What is the hydrogen ion concentration of a lake with a pH of 7.0?

10-7

400

What are the four major parts of an amino acid?

Amino group, carboxyl group, alpha carbon (and an attached hydrogen), and R-group

400

Which level of protein structure is most directly affected by a change in the amino acid sequence?

Primary structure

400

Why does water turn when going through the APN complex?

APN complex contains an asparagine that forms specific hydrogen bonds with the carbonyl oxygen and the side-chain amino group

500

What is the difference between polar and non-polar covalent bonds?

Polar: electrons hang out in an uneven distribution determined by the electronegativity of the atoms in the bond (unequal sharing of electrons)

Non-polar: electrons hang out in an even distribution in the bond (equal sharing of electrons)

500

In order to raise the pH of a solution, ____ is added to _____ the concentration of _____ ions in the solution.

a base; reduce; hydrogen

500

Evaluate this amino acid: Tryptophan

(I will pull up a picture)

Non polar :3

(not charged)

500

What bonds make up quaternary structure?

Hydrogen bonds, ionic bonds, Van der waals interactions (hydrophobic interactions), and disulfide bridges

500

Why is asparagine key to aquaporin?

Specificity for water

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