have so much in common
Nondisjunction in meiosis 1 results in this many abnormal gametes
What is 4?
This explains the mechanism of Mendelian inheritance
What is the Boveri-Sutton Chromosomal Theory of Inheritance
This scientist successfully demonstrated homologous recombination with fruit flies
Who is Stern
Trisomy 21 is also known as this
What is Down Syndrome
With regard to the fruit fly experiments, flies are carrying this type of chromosomes
What is recombinant
The arrow points to this enzyme synthesizing the leading strand continuously
What is DNA pol III
These pieces of replicated DNA come in pieces 100-200 nucleotides long
What are Okazaki Fragments
This arm is the longer arm of the chromosome
What is the q arm
Walter Sutton performed experiments on this animal proving that chromosomes separate into daughter cells during meiosis
What are grasshoppers
This Nobel Prize winner discovered how the enzyme telomerase works
Who is Blackburn
Individuals with the correct number of chromosomes are considered euploid, while those with incorrect number of chromosomes for their species are considered this
What is aneuploid
These can be bred every two weeks and only have 4 pairs of chromosomes
What are fruit flies
The green arrow points to this enzyme synthesizing short RNA primers?
What is primase?
Lagging strand replication on Okazaki fragments begins near this
What is the leading strand
This results in two gametes that are n+1 and two gametes that are n-1
What is nondisjunction during meiosis 1 (slide 19, ch13)
This is the result of the discovery that the closer genes are situated with one another on a chromosome the less likely they will experience crossover
What is linkage?
This scientist was able to show chromosomal crossover using corn
Who is McClintock
The XO genotype is also known as this
What is Turner's syndrome?
The green star is over the representation of a fly with a gray body and what king of wings?
What is vestigial (slide 11 ch13)
The arrow is pointing to this
What is the sliding clamp?
These found on the ends of DNA in humans consist of TTAGGG repeated 100-1000 times
What are telomeres
These contain the same location of centromeres, same length, and the same gene length
What are chromosomes
What is the Boverian-Sutton Theory of Inheritance
What is a karyogram
When a segment of a chromosome breaks off and attaches to a nonhomologous chromosome the result is this
What is translocation
The green star in the picture is around this
What is the recombination frequency percentage
The green arrow is pointing at this joining enzyme
What is ligase
In total, we likely have 50 million these
What are Okazaki fragments
Inactivation of this can lead to female cats having fabulous fur, while the males are plain Janes
What is an X chromosome?
Using new technology in the late 1800's, scientists were able to observe these changing shape during cell division and meiosis, and noticed them taking on an X shape
What are chromosomes
This scientist was able to successfully show that embryos in sea urchins would not develop in the absence of chromosomes
Who is Boveri?
This syndrome is due to XXY chromosome in males
What is Klinefelter syndrome
This young scientist created the first chromosome map using fruit flies
Who is Sturtevant?
The green arrow is pointing at this enzyme, whose duty it is to rip and replace RNA primers with DNA (or dNTPs)
What is DNA pol I
DNA runs 5' to 3' in this fashion
What is antiparallel
This results in one gamete that is n-1, one gamete is n+1, and two gametes are n
What is nondisjunction in meiosis 2? (slide 19, ch 13)
When they stole the credit for the experiments Dr. Rosalind Franklin performed with X-ray crystallography and diffraction, Watson, Crick and Wilkins won this in 1962
What is the Nobel Prize
This scientist isolated phosphate rich chemicals now known as DNA
Who was Meister?
This hybrid protein is a tyrosine kinase signaling protein
What is BCR-ABL
Results from the fly experiments were gathered and mulled over by Alfred Sturtevant, who created the first this
What is a chromosome map?
The green arrow is pointing at this enzyme that must synthesize DNA starting at 3' end of the primer, and goes in the 5' - 3' direction
What is DNA pol III
The 3' the represents the third this, and is where the covalent link to an alpha phosphate happens
What is carbon
When a Barr Body is activated, all cells derived from it contain this
What is the same deactivation
This amazing scientist died of ovarian cancer due to the extensive research that incorporated X-rays
Who is the amazing Rosalind Franklin who wasn't a jerk
Franklin's work was poached by these jerks
Who are Watson and Crick
The reciprocal translocation of genetic material between chromosomes 9 and 22 result in a larger and much smaller chromosome. The smaller chromosome is a diagnostic marker for this
What is leukemia
The green star is over this type
What is parental type
This requires a 3' hydroxyl to add a new dNTP
What is DNA pol III
During DNA replication, mistakes are only made at a ratio of 1:100,000, but when they are made, these can repair them
What are endonucleases?