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List each of the 5 WBC types found in peripheral blood and explain the features that help to identify each of them.
Neutrophils – most common, 10-12uM, multi-lobed nucleus, small granules in cytoplasm, polymorphonuclear cells, 8-10 hours in circulation, bacterial and fungi infections
Eosinophils – bi-lobed nucleus, 10-12uM, large and strongly staining cytoplasm granules, circulate 4-5 hours, defence against parasitic infections, and dampen allergic responses
Basophils – least commin, 8-10uM, 2-4 lobes in nucleus, large cytoplasmic granules (dark staining)
Lymphocytes – second most common, 10-12uM, large round nucleus/less cytoplasm, lifespan few days – years, T-lymphocytes = cell mediated immunity, B-lymphocytes = humoral immunity
Monocytes – largest 16-22uM, kidney shaped nucleus, circulate 10 hours, exit into tissues and become macrophages, removal of aged RBC’s and other debris, antigen processing, presentation to T lymphocytes