understanding cancer
cancer + cell biology
cancer as a multistep process
cancer prevention + detection
cancer treatment + research
100

What is cancer?

a disease where cells divide uncontrollably + invade other tissues

100

What is the normal way that cells die?

apoptosis

100

How does cancer normally begin?

a single cell undergoing a mutation that disrupts normal cell growth

100

What is cancer prevention?

actions taken to lower the risk of getting cancer

100

Name 2 therapies used to treat cancer.

surgery, radiation, chemotherapy, hormone therapy, immunotherapy

200

Where in the leading causes of death in the US does cancer rank?

2nd

200

What is a proto-oncogene?

a gene that stimulates cell growth + division

200

What can trigger a cancerous mutation?

exposure to carcinogens (tobacco smoke, UV radiation, certain chemicals)
200

What are 2 ways to prevent cancer?

healthy lifestyle choices, vaccinations, cancer screenings, medications
200
What do cancer treatments target?

tumor-suppressor genes (to prevent uncontrolled growth)

300

What is a tumor?

a mass of tissue caused by uncontrolled cell growth

300

A tumor functions similarly to what? (has it's own blood supply, tissues, and growth factors)

an organ

300

What are DNA segments at the end of chromosomes that eventually trigger the cell to stop dividing?

telomeres

300

How many of all cancer cases are due to individual behaviors? (tobacco use, poor diet, excessive UV radiation, alcohol use)?

about 1/2

300

How is gene therapy used in cancer treatment?

targets particular genes where the cancer is occurring

400

What is a benign tumor?

a tumor that isn't cancerous and doesn't spread to other body parts

400

What's the difference between a monoclonal and a polyclonal tumor?

monoclonal- from one cell

polyclonal- from many different cells

400

Does cancer develop all at once?

no, it grows as the cells keep uncontrollably dividing

400
Who is most qualified to promote cancer prevention?

healthcare workers/providers

400

What is the goal of cancer research?

to diagnose and treat cancer as early as possible

500

What is the difference between a malignant and a metastatic tumor?

metastatic tumors have already spread to other parts of the body + are more harmful

500

Name one way a cancerous cell is different from a normal cell.

larger/multiple nuclei, grows faster + without control, can send signals to other cells, smaller cytoplasm, coarse chromatin

500

True or False: It never takes more than a couple of years for cancer to become malignant.

false, it can take decades to grow to that state
500

How does the US government play a role in cancer prevention/detection?

public policy regulations and investing in research to advance biomedical technologies that can detect and prevent cancer

500

Why do we need to improve cancer research?

to minimize damage done to healthy cells around the cancer cells

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