Human Genome Introduction
How would you define the genome
A map of all the genetic information found in humans
What was the first mammalian organism to have its genetic sequence fully decoded?
Mouse
In what year was the human genome project supposed to be completed? When was it completed?
2005- actually completed 2003
Aside from a mouse what other animals have had their genomes sequenced
Chimpanzee, Honeybee, Opossum
If an electric train is going south, what direction is the smoke going?
What is another name for a base in DNA
Nucleotides
What was the final cost per base of sequencing the Human Genome Project
9 cents per base
How many genes control for cystic fibrosis? Which gene controls it?
CFTR gene
What are the 3 types of cancers sequenced after the completion of the human genome project
There is only one word spelled wrong in the dictionary. What is it?
Wrong
How are DNA sequences typically written
In pairs
How many years did scientists anticipate it taking to complete the human genome project? How many years did it actually take to sequence the human genome
They thought it would be 15 years, however it actually took 13 years
Who was Celera Genomics Corporation?
A private gene sequencing company that originally completed with the human genome project. Later they joined the project to work towards completing the sequencing more quickly
How many genes do humans have?
30,000-40,000
Define prophylactic
Preventative
What are the names of the nucleotides that make up DNA? Which bases are matched together
Adenine <--> Thymine
Cytosine <--> Guanine
What was the ideal (original) cost or completing the sequencing of the human genome?
25 cents per base
Who was Craig Venter
The founder of Celera Genomics Corporation
What is a SNP?
Single Nucleotide Polymorphism. Sites where DNA sequences differ by a single base
What are we currently able to use genetic testing for?
Treatment of disease, cancer prevention
What is PCR technology and when was it created?
1983
When did discussion of the human genome project begin?
1984
What method of sequencing did Celera Genomics Corporation use?
Whole Genome Shotgun Method
A database of human genetic variation
What are the potential benefits of future genetic research?
Prophylactic illness treatment, cancer treatment, side effect prevention, treatment of genetic diseases