C. Elegans & Ascidians
Sea Urchins
Xenopus
Chicken
Mammals
100

These proteins ensure that the first division in C. elegans development is asymmetric.

What are PAR proteins?

100

This cleavage pattern is seen in Sea Urchins embryos, producing macromeres and micromeres.

What is radial cleavage?

100

This term describes the darkly pigmented half of a Xenopus egg.

What is the animal pole?

100

This term describes the movement of cells during primitive streak formation.

What is ingression?

100

This process, seen in mice embryos, inverts the embryo.

What is "turning"?

200

These mRNAs and proteins localize to the posterior end of the embryo before the first cell division, and are determinants for the germ line.

What are P granules?

200

These small cells act as inducers for gut formation.

What are micromeres?

200

This signaling center is thought to be an earlier developmental stage of the Spemann-Mangold organizer.

What is the Nieuwkoop center?

200

This layer of cells becomes displaced by the endoblast later in development.

What is the hypoblast?

200

This process creates the morula.

What is compaction?

300
In sea squirts, this "yellow cytoplasm" is a maternally supplied determinant of muscle cells.

What is myoplasm?

300

This chemical is used to activate the Wnt pathway, regardless if a Wnt signal is actually present.

What is LiCl?

300

This structure forms in the midline of an embryo during neurulation.

What is the notochord?

300

During neurulation, this structure regresses and leaves behind cells specified to become the head, notochord, and somites.

What is Hensen's node?

300

This mass of cells will give rise to the entire embryo (not including extra-embryonic structures).

What is the Inner Cell Mass (ICM)?

400

This signaling molecule is important for specifying  notochord cell fate in ascidians. 

What is FGF (fibroblast growth factor)?

400

Following gastrulation and the formation of a mouth, this new axis is defined.

What is the oral/aboral axis?

400

These blocks of tissue give rise to muscle and skeleton.

What are somites?

400

During primitive streak formation, this protein antagonizes Nodal signaling from epiblast cells.

What is Cerberus?

400

During the formation of the left-right axis, the coordinated beating of cilia and an increase in intracellular Ca2+ leads to the upregulation of this signaling molecule.

What is Nodal?

500

In a 4-celled C. elegans embryo, this cell would not be able to divide asymmetrically if Wnt/MOM-2 signaling was blocked. 

What is the EMS cell?

500

This term is used to described the state of a Sea Urchin embryo when Wnt signaling is activated throughout the entire embryo.

What is "vegetalized"?
500

During cortical rotation, these two maternal factors are moved to the dorsal side of the embryo.

What are Xwnt-11 mRNAs and Dishevelled proteins?

500

These two signaling molecules belong to the TGF-B family and are involved in the formation of the primitive streak.

What are Nodal and Vg-1?

500

In chicks, the hypoblast prevents primitive streak formation by inhibiting Nodal signals. In mammals, these two structures accomplish the same goal.

What are the DVE and the AVE?

(distal visceral endoderm and anterior visceral endoderm)

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