HSS
The population health measure which describe a rate of new cases over a time rather than an instantaneous snapshot of them.
What is incidence?
What are smoking, diabetes, hypertension, and hyperlipidemia?
The only type of hypersensitivity which does NOT involve antibodies.
What is a Type IV Hypersensitivity reaction?
The three most common trisomy diseases, and their corresponding abnormal chromosomes.
This continent is the primary source of information for GWAS (Genome Wide Association Studies).
What is Europe?
This type of false test result is unlikely in a test with high specificity.
What is a false positive?
The mechanism of hypercoagulability due to Factor V Leiden.
What is resistance to Protein C cleavage due to mutation of cleavage site on Factor V?
The five cardinal signs of inflammation.
What are dolor (pain), calor (heat), rubor (redness), tumor (swelling), and functio laesa (loss of function)?
Parental DNA that is ALWAYS imprinted in Angelman syndrome.
What is paternal DNA?
The mathematical term the Hardy Weinberg equilibrium uses to define the frequency of recessive allele carriers in the population.
What is "2pq"?
The statistical error type which is related to power.
What is Type II (beta) error?
1-Beta = Power
The hemostatic process blocked/inhibited by ADP receptor antagonists such a Clopidogrel.
What is platelet aggregation?
Three key "cascades"/key mediators activated by Hageman factor, and their corresponding effects.
What are: Kinin cascade leading to bronchospasm, vasc. permeability, and pain; clotting factor cascade leading to fibrin clot assembly; and plasmin activation leading to fibrin breakdown and complement activation?
The distinguishing factor between "aplasia" and "agenesis."
What is the presence of primordial tissue? (Agenesis =no precursor tissue, aplasia = failure to develop from existing precursor tissue).
The representation of monozygotic twins in a pedigree.
What is an inverted V with a line?
Under this circumstance, it is appropriate to use odds to calculate risk.
What is low overall prevalence/risk?
Macrophage products which degrade the ECM of blood vessels in the setting of atherosclerosis.
What are matrix metalloproteases?
What is maternal (Rh-) Type II Hypersensitivity reaction to SECOND child (Rh+) blood?
First pregnancy with Rh+ child primes parental response to D antigen of Rh+ blood
This microdeletion syndrome is associated with Omphalocele.
What is Beckwith-Wiedeman syndrome?
The mechanism of action of Imatinib, used to treat Chronic Myelogenous Leukemia.
What is inhibition of constitutively active Bcr-Abl, a mutant constitutively active tyrosine kinase?
The definition of p value.
What is the probability, given that the null hypothesis is true, of observing the experimental data distribution at hand or a more extreme one?
This interaction allows someone with dysfunctional Hageman factor to utilize their intrinsic clotting pathway.
What is cross-activation of Factor IX by Factor VII?
Persistent inflammatory condition identifiable by Rokitansky-Aschoff sinuses.
What is Chronic cholecystitis?
This treatment reveals abnormal methylation patterns in imprinting diseases such as Prader-Willi syndrome.
What is bisulfite DNA treatment?
The probability of being an asymptomatic carrier of achondroplasia, where the incidence is 1/25,000