ABO System
Blood Components
Transfusion Reactions
Babies
Name that Null!
100

This is the characteristic color used to identify anti-B.

What is yellow

100

This modified red blood cell product is prepared by removing most plasma proteins, reducing the risk of allergic transfusion reactions and preventing complications in IgA-deficient patients.

What are washed RBCs

100

This transfusion reaction is characterized by hives and itching

What is urticarial / allergic reaction

100

A screening test used to detect Fetal-Maternal Hemorrhage. Able to detect a bleed of 10mL or more

What is the Rosette Test

100

This null phenotype, marked by the absence of both common antigens in its system, is associated with resistance to Plasmodium vivax infection.

What is Duffy null

Fy(a-b-)

200

Offspring can potentially express all four common blood types when parents with these two phenotypes are paired.

What is A and B

200

This blood product is created by combining packed red blood cells with plasma to approximate whole blood, often used in exchange transfusions or neonatal transfusion scenarios.

What are reconstituted RBCs

200

Anaphylactic transfusion reactions may occur in patients with a deficiency of this immunoglobulin.

What is IgA

200

This condition is caused by maternal antibodies against antigens on fetal red cells inherited from the father

What is Hemolytic Disease of the Fetus and Newborn (HDFN)

200

This extremely rare null phenotype, defined by the absence of the H antigen and associated with a naturally occurring hemolytic anti-H, requires individuals to receive transfusions only from others with the same phenotype

What is the Bombay phenotype

300

These red blood cells show the strongest agglutination when tested with Ulex europaeus lectin

 

What are group O red blood cells?

300

This blood product, rich in fibrinogen, factor VIII, von Willebrand factor, and factor XIII, is commonly used to treat hypofibrinogenemia.

What is Cryoprecipitate 

300

A quick way to assess for a possible acute hemolytic transfusion reaction is to spin down a post-reaction specimen and look for this

What is hemolysis

300

One dose of Rh immune globulin will protect the mother from a whole blood bleed up to this amount

What is 30mL

300

This null phenotype produces red blood cells resistant to lysis in 2M urea, and is found in Polynesian populations.

What is Jk null

Jk(a-b-)

400

This approximate percentage represents how many individuals with group A can be further classified as subgroup A1.

What is 80% of group A individuals

400

Red blood cells preserved for long-term frozen storage must be kept under this ultra-low temperature condition, typically at or below this value.

What is ≤ -65°C

400

Clinical signs of this reaction include chills, shock, flank pain, renal failure and DIC. This type of reaction is often due to clerical error.

What is an Acute Hemolytic Transfusion Reaction

400

Toxic levels of unconjugated bilirubin in an infant's brain is called

What is Kernicterus

400

This null phenotype occurs in a blood group system whose antigens are expressed in body fluids like saliva and are closely associated with an individual’s secretor status.

What is Lewis null

Le(a-b-)

500

The presence of blood group A is confirmed by detecting this specific immunodominant sugar molecule on the red cell surface

N-acetyl-D-galactosamine

500

Apheresis platelets must maintain a pH of at least this value at the end of their storage period to remain acceptable for transfusion

What is 6.2

500

This serious transfusion reaction is characterized by acute lung injury, hypoxemia, and non-cardiogenic pulmonary edema occurring within six hours of transfusion

What is TRALI

500

This elution method uses freezing and thawing to disrupt antigen-antibody interactions on red blood cells, commonly used to recover bound antibodies such as in cases of hemolytic disease of the newborn

What is Lui Freeze-Thaw Elution

500

This null phenotype results in red blood cells lacking Glycophorin A and Glycophorin B, eliminating all antigens carried on those structures and effectively removing an entire blood group system.

 

What is the MkMk phenotype

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